Antibodies to Symmetrically Dimethylated Arginine Analytes and Use Thereof

A method for determining an amount of at least one symmetrically dimethylated arginine analyte in a medium, the method comprising:

• combining in a medium:
• a sample suspected of containing at least one symmetrically dimethylated arginine analyte, and
• a compound of Formula 1;
• and
• detecting the presence of an enzymatic reaction product of the compound, wherein an increase in the enzymatic reaction product of the compound indicates the presence of the symmetrically dimethylated arginine analyte in the sample, and
• wherein the compound of Formula 1 comprises:
• wherein:
• R1 is —Y—Z;
• Y is a linking group;
• and
• Z is a label enzyme selected from the group consisting of an alkaline phosphatase, a β-galactosidase, and a horseradish peroxidase.