Butenolide compounds containing thiazolidinone structure as well as preparation method therefor and use thereof

A butenolide compound containing a thiazolidinone structure, represented by the following general formula:

• in the formula:
• R1 and R2 are each independently selected from hydrogen and C1-C12 alkyl;
• or, R1 and R2, together with the carbon atom bonded therewith, form C3-C12 cycloalkyl or C3-C12 cyclic heteroalkyl, heteroatom in the heteroalkyl is N, O, or S, wherein the hydrogen in the C3-C12 cycloalkyl or the C3-C12 cyclic heteroalkyl may be monosubstituted or polysubstituted by R5;
• R3 is selected from hydrogen, hydroxyl, C1-C12 alkyl, C5-C7 cycloalkyl, unsubstituted aryl or heteroaryl, or aryl or heteroaryl containing one to three R6 substituents;
• R4 is selected from C1-C12 alkyl, halogenated C1-C12 alkyl, C1-C12 alkoxy, halogenated C1-C12 alkoxy, C3-C12 cycloalkyl, aryl or heteroaryl substituted by one to three R6, or biphenyl- or phenoxyphenyl substituted by one or more R6;
• R5 is selected from hydroxyl, carbonyl, methoxy, methoxyoximido, formyl, halogen, C1-C12 alkyl, halogenated C1-C12 alkyl, C1-C12 alkoxy, or halogenated C1-C12 alkoxy;
• and
• R6 is selected from halogen, hydroxyl, amino, cyano, nitro, C1-C12 alkyl, halogenated C1-C12 alkyl, C1-C12 alkoxy, halogenated C1-C12 alkoxy, C3-C12 cycloalkyl, C1-C12 alkylthio, halogenated C1-C12 alkylthio, C1-C12 alkylamino, halogenated C1-C12 alkylamino, di(C1-C12 alkyl)amino, halogenated di(C1-C12 alkyl)amino, C2-C12 alkenyl, C2-C12 alkynyl, C2-C12 alkenoxy, halogenated C2-C12 alkenoxy, C2-C12 alkynyloxy, halogenated C2-C12 alkynyloxy, C1-C12 alkylsulfonyl, halogenated C1-C12 alkylsulfonyl, C1-C12 alkylcarbonyl, halogenated C1-C12 alkylcarbonyl, C1-C12 alkoxycarbonyl, halogenated C1-C12 alkoxycarbonyl, C1-C12 alkoxy C1-C12 alkyl, halogenated C1-C12 alkoxy C1-C12 alkyl, C1-C12 alkylthio C1-C12 alkyl, halogenated C1-C12 alkylthio C1-C12 alkyl, C1-C12 alkoxycarbonyl C1-C12 alkyl, halogenated C1-C12 alkoxycarbonyl C1-C12 alkyl, C1-C12 alkylthiocarbonyl C1-C12 alkyl, halogenated C1-C12 alkylthiocarbonyl C1-C12 alkyl, C1-C12 alkylcarbonyloxy, halogenated C1-C12 alkylcarbonyloxy, C1-C12 alkoxycarbonyloxy, halogenated C1-C12 alkoxycarbonyloxy, C1-C12 alkylsulfonyloxy, halogenated C1-C12 alkylsulfonyloxy, C1-C12 alkoxy C1-C12 alkoxy or halogenated C1-C12 alkoxy C1-C12 alkoxy.