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US 2026/0109664 A1Published application
Compounds for use as medicaments
AssigneeChariot Innovations Ltd
InventorsLisa Dawson, Mark Harrison
Life of this patent
Estimating the term…
Abstract
The application relates to compound of Formula (I) or a pharmaceutically acceptable salt, solvate or prodrug thereof, for use as a medicament.
Claims16
A compound of Formula (I):
- or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein:
- Q is a substituted or unsubstituted cyclic group;
- each of R1 and R2 together represent ═O or is independently selected from —H, —Rα, —Cl, —Br, —I, —F, —OH, —RαOH, —OC(O)Rα, —ORα, —OCH2NHRα, —OCHRαNRα2, —OCH2RαNHRα, —NO2, —NH2, —N3, —SH, —SO2H, —SO2NH2, —CO2H, —RαCN, —CN, —C(O)NH2, —C(O)NHRα, —C(O)NRα2, —C(O)ORα, —Rα C(O)ORα, —Rα C(O)OH, —CH3, —CnH2n-2(O)NH2, —CnH2n-2(O)NHRα, or —CnH2n-2(O)NRαRα;
- and
- R3 is independently selected from —H, —Rα, —Cl, —Br, —I, —F, —OH, —RαOH, —OC(O)Rα, —ORα, —OCH2NHRα, —OCHRαNRα2, —OCH2RαNHRα, —NO2, —NH2, —N3, —SH, —SO2H, —SO2NH2, —CO2H, —RαCN, —CN, —C(O)NH2, —C(O)NHRα, —C(O)NRα2, —C(O)ORα, Rα C(O)ORα, Rα C(O)OH, —CH3, —CnH2n-2(O)NH2, —CnH2n-2(O)NHRα, or —CnH2n-2(O)NRαRα;
- wherein each Rα is independently selected from a methylene C1-C20 alkyl, C2-C20 alkenyl, C2-C20 alkynyl or C3-C20 cyclic group;
- wherein any —Rα may optionally be substituted with one or more methylene, C1-C4 alkyl, C1-C4 haloalkyl, C3-C7 cycloalkyl, —O(C1-C4 alkyl), —O(C1-C4 haloalkyl), —O(C3-C7 cycloalkyl), halo, —OH, —NH2, —CN, —NO2, —C≡CH, —CHO, —CON(CH3)2 or oxo (═O) groups and wherein each n is independently an integer from 1 to 20.
4 more elements
Dependencies are inferred from the claim text.