Demineralized bone fiber composition for use in minimally invasive surgery
AssigneeArteriocyte Medical Systems, Inc.
InventorsNelson SCARBOROUGH, Andrew J. CARTER, Bradley E. PATT
Life of this patent
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Abstract
A pharmaceutical composition for treating moderate or severe rosacea comprises a formulated, body weight-independent low dose of minocycline that reduces the severity of rosacea in at least 2 weeks with a decrease in lesion count, Investigator's Global Assessment (IGA) score, and Clinician's Erythema Assessment (CEA) score with a measured improvement in quality of life.
Claims21
A bone implant comprising a sheet of demineralized bone fibers (DBF), the sheet of DBF comprising a plurality of elongated bone fibers cut from demineralized bone in a direction parallel to the orientation of collagen fibers, the bone implant comprising:
- a hollow tube or a cylinder shaped implant formed from rolling the sheet of DBF, wherein the hollow tube or cylinder shaped implant has a length of from about 1 cm to about 30 cm and a diameter of from about 3 mm to about 15 mm;
- or
- a bone implant bag formed from bonding a first sheet of DBF with a second sheet of DBF.
A bone implant made from a sheet of demineralized bone fibers (DBF) comprising a plurality of elongated bone fibers cut from demineralized bone in a direction parallel to the orientation of collagen fibers, the method comprising:
- providing the DBF into a sheet mold to form a sheet of DBF;
- and
- processing the sheet of DBF by:
- i) rolling the sheet of DBF to form a cylindrical bone implant or a hollow tube bone implant;
- or
- ii) bonding a first sheet of DBF with a second sheet DBF to form a bone implant bag,
- wherein the hollow tube bone implant or the cylindrical bone implant has a length of from about 1 cm to about 30 cm and a diameter of from about 3 mm to about 15 mm.
A method of making a bone implant bag made from a sheet of demineralized bone fibers (DBF), the method comprising:
- providing the DBF into a sheet mold to form a sheet of DBF;
- and
- bonding a first sheet of DBF with a second sheet DBF to form the bone implant bag.
A method of making a bone implant for minimally invasive surgery (MIS), comprising:
- compressing a first bone material into a mold to form a sheet of compressed bone material;
- and
- rolling the sheet to form a cylindrical bone implant.
Dependencies are inferred from the claim text.