Aerosol generating material in discrete portions comprising a substituted 3-(1-methylpyrrolidin-2-yl)pyridine compound
AssigneeRAI Strategic Holdings, Inc.
InventorsKyle Ford, Brandon S. Darrow, Michael R. Galloway, Gary M. Dull
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Abstract
Disclosed herein is a consumable including one or more discrete portions of aerosol generating material. The aerosol generating material includes an aerosol former, a binder, and an active agent, wherein the active agent includes at least a substituted 3-(1-methylpyrrolidin-2-yl)pyridine, 3-(azetidin-2-yl)pyridine, or 3-(azetidin-2-ylmethoxy)pyridine. Further provided is a non-combustible aerosol provision system including the consumable.
Claims19
A consumable comprising one or more discrete portions of aerosol generating material, the aerosol generating material comprising an aerosol former, a binder, and an active agent, the active agent comprising at least a compound having a structure according to Formula I, Formula II, or Formula III:
- wherein R1, R2, R3, and R4 are each independently selected from the group consisting of hydrogen, alkyl, alkoxy, cycloalkyl, alkenyl, alkynyl, aryl, alkylaryl, amino, halogen, and cyano, wherein any of said alkyl, alkoxy, cycloalkyl, alkenyl, alkenyl, alkynyl, aryl, alkylaryl, and amino may optionally be substituted;
- and wherein at least one of R1, R2, R3, and R4 are not hydrogen;
- or
- wherein:
- R5 and R6 are each independently selected from the group consisting of hydrogen, alkyl, alkoxy, cycloalkyl, alkenyl, alkynyl, aryl, alkylaryl, amino, halogen, and cyano, wherein any of said alkyl, alkoxy, cycloalkyl, alkenyl, alkenyl, alkynyl, aryl, alkylaryl, and amino may optionally be substituted;
- R7 is selected from the group consisting of hydrogen and CH3;
- R8 is selected from the group consisting of hydrogen and C1-C3 alkyl;
- and
- at least one of R7 and R8 is not hydrogen;
- or
- wherein
- L is a bond or —OCH2—*, where the asterisk indicates an attachment point to the azetidine ring;
- R9, R10, R11, and R12 are each independently selected from the group consisting of hydrogen, alkyl, alkoxy, halogen, and cyano;
- R13 is H or CH3;
- and
- R14 is H or CH3.
Dependencies are inferred from the claim text.