Neuregulin and use thereof
AssigneeZensun (Shanghai) Science & Technology, Co., Ltd.
InventorMingdong ZHOU
Life of this patent
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Abstract
Provided is use of a neuregulin or a functional fragment thereof, or a nucleic acid encoding a neuregulin or a functional fragment thereof, or a substance for improving the yield and/or function of a neuregulin in a human body in the preparation of a medicament for preventing, treating or delaying the onset of heart failure in a heart failure patient. The medicament can improve the cardiac function of the heart failure patient and reverse ventricular remodeling. Also provided are a method and device for preventing and treating a heart failure patient or delaying the onset of heart failure in a heart failure patient.
Claims44
Use of a neuregulin or a functional fragment thereof, or a nucleic acid encoding the neuregulin or a functional fragment thereof, or a substance that enhances the production and/or function of the neuregulin in the human body, in the preparation of a drug for preventing, treating a patient with heart failure, or delaying the onset of heart failure in a patient, and the drug can improve cardiac function in a patient with heart failure.
Use of the neuregulin in the preparation of a drug for preventing, treating a patient with heart failure, delaying the onset of heart failure in a patient, or improving cardiac function in a patient with heart failure.
A method for preventing, treating a patient with heart failure, or delaying the onset of heart failure in a patient, comprising administering to a patient in need thereof an effective amount of neuregulin or a functional fragment thereof, or a nucleic acid encoding the neuregulin or a functional fragment thereof, or a substance that enhances the production and/or function of the neuregulin in the human body, and the method can improve cardiac function in the patients with heart failure.
A method for preventing, treating a patient with heart failure, delaying the onset of heart failure in a patient, or improving cardiac function in a patient with heart failure, comprising administering to a patient in need thereof an effective amount of neuregulin.
Dependencies are inferred from the claim text.