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US 2026/0103467 A1Published application
Salts of an fgfr inhibitor
AssigneeIncyte Corporation
InventorsZhongjiang Jia, Jiacheng Zhou, Qun Li
Life of this patent
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Abstract
The present invention relates to salt forms of the Fibroblast Growth Factor Receptors (FGFR) inhibitor 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholin-4-ylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidin-2-one, including methods of preparation thereof, where the compound is useful in the treatment of FGFR mediated diseases such as cancer.
Claims21
A salt which is an acid salt of 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholin-4-ylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidin-2-one, having the structure:
- or a hydrate or solvate thereof, wherein the acid is fumaric acid.
(canceled)
7-24. (canceled)
Dependencies are inferred from the claim text.