Adjuvants for enhancing the immune response
AssigneesLankenau Institute for Medical Research, The Regents of the University of California
InventorsEllen Heber-Katz, Sam Bollinger, Benjamin Cameron, Phillip B. Messersmith
Life of this patent
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Abstract
Compositions and methods enhancing a patient's immune response to an immune stimulatory composition are disclosed. In certain embodiments, the method includes administering a composition comprising a PHD pathway inhibitor and a vaccine to a subject.
Claims28
A method for enhancing a patient's immune response to an immune stimulatory composition, the method comprising administering an immune stimulatory composition and at least one agent that affects metabolic reprogramming.
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A method of enhancing an immune response, the method comprising administering a PHD inhibitor in combination with a vaccine, wherein the treatment increases the strength and/or potency of the immune response when compared to administration of a vaccine without a PHD inhibitor.
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A composition comprising a vaccine and an adjuvant selected from at least one agent that affects metabolic reprogramming.
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Dependencies are inferred from the claim text.