Treatment methods
AssigneeLevon Michael Khachigian
InventorsLevon Michael KHACHIGIAN, Sebastian M. MARCUCCIO
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Abstract
A method of reducing vascular permeability, neovascularisation, angiogenesis, inflammation, cell migration and/or proliferation, including administering an effective amount of an inhibitor of FosB/ΔFosB expression and/or VCAM-1 expression and/or ERK1/2 phosphorylation, and pharmaceutical compositions and kits comprising inhibitors of FosB/ΔFosB expression and/or VCAM-1 expression and/or ERK1/2 phosphorylation.
Claims12
A pharmaceutical composition comprising a compound of formula II, or a pharmaceutically acceptable salt thereof:
- wherein:
- R3 is straight or branched C1-C6 alkyl;
- and
- R4 is straight or branched
- C1-C6 alkyl, or R4 is
- wherein q is 1, 2, 3 or 4;
- and R5 is straight or branched C1-C6 alkyl, and a pharmaceutically acceptable carrier.
A pharmaceutical composition comprising a compound of the following formula:
- or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.