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US 2026/0102344 A1Published application
Metered dose inhalers and suspension compositions
AssigneeKindeva Drug Delivery L.P.
InventorsPhilip Cocks, Alexander Slowey, Benjamin Myatt, Sarah Wrigglesworth, James Lister
Life of this patent
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Abstract
Various embodiments of a metered dose inhaler are disclosed. The inhaler includes a metering valve, a canister, and an actuator having an actuator nozzle. The canister includes a formulation having greater than 70% by weight of HFO-1234ze(E), and at least one active pharmaceutical ingredient suspended in the formulation to form a suspension.
Claims20
A metered dose inhaler comprising:
- a metering valve;
- a canister;
- and
- an actuator comprising an actuator nozzle;
- wherein the canister comprises a formulation, the formulation comprising:
- greater than 70% by weight of propellant HFO-1234ze(E);
- ethanol;
- and
- at least one active pharmaceutical ingredient suspended in the formulation to form a suspension.
6 more elements
A metered dose inhaler comprising:
- a metering valve;
- a canister;
- and
- an actuator comprising an actuator nozzle;
- wherein the canister comprises a formulation, the formulation comprising:
- a propellant comprising HFO-1234ze(E);
- ethanol;
- and
- an active pharmaceutical ingredient comprising fluticasone or a pharmaceutically acceptable salt or ester thereof, wherein the fluticasone or pharmaceutically acceptable salt or ester thereof is suspended in the formulation to form a suspension.
6 more elements
A metered dose inhaler comprising:
- a metering valve;
- a canister;
- and
- an actuator comprising an actuator nozzle;
- wherein the canister comprises a formulation, the formulation comprising:
- a propellant comprising HFO-1234ze(E);
- ethanol;
- and
- an active pharmaceutical ingredient comprising salbutamol or a pharmaceutically acceptable salt or ester thereof, wherein the salbutamol or pharmaceutically acceptable salt or ester thereof is suspended in the formulation to form a suspension.
6 more elements
A metered dose inhaler comprising:
- a metering valve;
- a canister;
- and
- an actuator comprising an actuator nozzle;
- wherein the canister comprises a formulation, the formulation comprising:
- a propellant comprising HFO-1234ze(E);
- ethanol;
- and
- an active pharmaceutical ingredient comprising mometasone or a pharmaceutically acceptable salt or ester thereof, wherein the mometasone or pharmaceutically acceptable salt or ester thereof is suspended in the formulation to form a suspension.
6 more elements
Dependencies are inferred from the claim text.