Catheter, system, and method for selective ablation in the mucosa and submucosa of the gastrointestinal tract

A catheter comprising:

• a probe having a proximal end, a distal end, and a body portion disposed between the proximal and distal ends;
• and
• a cryogenic supply assembly housed within the probe, said cryogenic supply assembly comprising a sprayer orifice assembly and a cryogenic supply line within the sprayer orifice assembly,
• wherein said sprayer orifice assembly comprises a sprayer tube and a seal chamber component, said sprayer tube comprising one or more sprayer orifices for delivery of a cryogenic fluid from the cryogenic supply line to the probe, and said seal chamber component comprises a seal chamber associated with each of the one or more sprayer orifices and forming a fluidic conduit between the cryogenic supply line and the one or more sprayer orifices through which the cryogenic fluid flows to the probe, and
• wherein said cryogenic supply assembly is configured so that the cryogenic supply line and the sprayer tube move either axially independent of one another or axially together as one unit.