A microfluidic cartridge for enriching a biological fluid

A microfluidic cartridge (100) for enriching a biological fluid of low viscosity, the cartridge (100) comprising:

• a base plate (1) defining a flow surface;
• a coverslip (5) positioned above the base plate (1), to define a chamber (2) on the flow surface of the base plate (1) for receiving the biological fluid containing a plurality of particles (10), the coverslip (5) is configured to conceal at least a portion of the chamber (2), wherein the chamber (2) is defined with a predefined height;
• an inlet section (3a) defined at one end (4a) of the chamber (2) for introducing the biological fluid;
• and
• an outlet section (3b) defined at another end (4b) opposite to the one end (4a) of the chamber (2) and extending beyond the coverslip (5), to draw the biological fluid under capillary action;
• characterized in that, the predefined height of the chamber (2) is at least two times the height of a group of large size particles in the plurality of particles (10) in the biological fluid, wherein the plurality of particles (10) of the biological fluid is enriched about the predefined height of the chamber (2), under gravity sedimentation over a predefined time to form a monolayer.