Method of vital pulp therapy using bioactive composites
AssigneeImam Abdulrahman Bin Faisal University
InventorsMohammed ALGHARNI, Omar OMAR, Fatimah DAHLAWI, Jehan ALHUMAID
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Abstract
A method of vital pulp therapy with a bioactive capping material. The method includes drilling into a pulp of a tooth having decay to form a hole, then excavating infected pulp from the hole. The bioactive capping material is prepared by mixing glass ionomer cement (GIC) and potassium nitrate (KNO3) with a solvent. The method further includes covering healthy pulp in the tooth with the bioactive capping material and curing the bioactive capping material to form a cured capping material. The bioactive capping material includes KNO3 in an amount of 1 to 10 percent by weight (wt. %) based on the weight of the capping material.
Claims20
A method of vital pulp therapy, comprising:
- drilling into a pulp of a tooth to form a hole, then excavating infected pulp from the hole, wherein the tooth has a cavity breaching at least a surface of the pulp and is under lipopolysaccharide (LPS) stimulation during the drilling;
- mixing a glass ionomer cement (GIC) and potassium nitrate (KNO3) with a solvent to form a bioactive capping material;
- and
- covering remaining healthy pulp in the hole of the tooth with the bioactive capping material and curing the bioactive capping material to form a cured capping material,
- wherein the KNO3 is present in the bioactive capping material in an amount of 1 to 10 wt. % based on the weight of the bioactive capping material, and
- wherein after the curing, the patient has an IL-6 secretion that is 40 to 75% less than the IL-6 secretion after curing with a substantially identical method using the same bioactive capping material without the KNO3.
A method of treating inflammation near a tooth comprising:
- drilling into a pulp of a tooth of a patient to form a hole, then excavating infected pulp from the hole, wherein the tooth has a cavity breaching at least a surface of the pulp;
- and
- administering a bioactive dental composite comprising a glass ionomer cement (GIC) and potassium nitrate to at least one surface of remaining healthy pulp of the tooth of a patient,
- wherein the potassium nitrate is present in an amount of 1 to 10 wt. % based on the weight of the dental composite, and
- wherein the dental composite promotes the release of a regenerative marker and inhibits the release of an inflammatory marker.
Dependencies are inferred from the claim text.