Back to results
US 2026/0083668 A1Published application
Orally administered corticosteroid compositions
AssigneeEllodi Pharmaceuticals, L.P.
InventorsStephen PERRETT, Fredric Jay COHEN, Gopi M. VENKATESH
Life of this patent
Estimating the term…
Abstract
The present invention is directed to orally administered corticosteroid compositions. The present invention also provides a method for treating a condition associated with inflammation of the gastrointestinal tract in an individual. The method comprises administering to an individual in need thereof a pharmaceutical composition of the present invention.
Claims21
An orally dispersing tablet comprising:
- (i) about 0.5 mg to about 1.5 mg of budesonide;
- and
- (ii) at least one pharmaceutically acceptable ingredient which facilitates the dispersal of the tablet in the oral cavity;
- and
- (iii) sucralose, mannitol, magnesium stearate, polyvinyl pyrrolidone, polyethylene glycol, or combinations thereof;
- wherein upon administration a therapeutically effective amount of budesonide is deposited topically in the esophagus,
- wherein the orally dispersing tablet disintegrates within 60 seconds when tested using the USP <701> Disintegration Test;
- and
- wherein the orally dispersing tablet has a hardness of 8-48 N or a friability of not more than 1%.
6 more elements
Dependencies are inferred from the claim text.