Topical delivery systems and methods of use
OwnerRoger H. Tallinventor
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Abstract
Topical delivery systems, multi-phase topical application formulations, and methods of use including combining multi-phase ingredients to form a first emulsified system, such as a pre-mixture hydrogel. A second emulsified system is formed to be combined with the pre-mixture hydrogel to form an emulsified topical application formulation. Additives and/or adjuvants are combined with the emulsified multi-phase formulation to form a delivery system. Delivery systems include a combined sustained-release, moisturizing barrier which may be applied to the skin. Multivesicular and/or multi-lamellar characteristics of the barrier provide for time-dependent effects, such as hair follicle softening and/or delayed active ingredient delivery.
Claims13
A multi-phase hydrogel, comprising:
- a first pre-mixture comprising a first plurality of ingredients, including water and a first polymer;
- a second pre-mixture comprising a second plurality of ingredients, including water and a second polymer;
- wherein at least one of the first polymer and the second polymer comprises modified potato starch.
A multiphase hydrogel formulation, comprising:
- a continuous phase having a first molecule of at least one of the general formulas:
- wherein Formula (1) a and b are any of 1 and 2;
- wherein Formula (2), R is Cr, where f is any number from 1 to 57;
- wherein c, d, and e, are any number 0, 1, to 104;
- and
- a dispersed phase having at least a second molecule and a third molecule, the first molecule comprising a general formula:
- wherein Formula (3), R is Ck, k is any number 3 to 57, l is any number 3 to 104, and m is any number 1 to 14;
- and
- wherein the third molecule has the Formula (3) where k is 6, l is 10, and m is 5 of a repeating polymeric chain.
A method of forming a hydrogel, comprising:
- forming a first pre-mixture comprising a first plurality of ingredients, including water and a first polymer;
- forming a second pre-mixture comprising a second plurality of ingredients, including water and a second polymer;
- emulsifying at least one of the first polymer and the second polymer by combining at least two of the first pre-mixture, the second pre-mixture, and a third pre-mixture, wherein the at least two of the first pre-mixture, the second pre-mixture, and a third pre-mixture comprises an esterified molecule.
Dependencies are inferred from the claim text.