US 2026/0078422 A1 · MICROORGANISMS FOR THE PRODUCTION OF LOW-CALORIE SUGARS

Microorganisms for the production of low-calorie sugars

AssigneeThe Regents of the University of California

InventorsShota ATSUMI, Justin Bloomfield SIEGEL, Angela ZHANG, Jayce Elizabeth TAYLOR, Jake Nicholas GONZALES, Dileep Sai Kumar PALUR, Timothy Anderson COULTHER, Amiruddin Bin Johan LECHNER, Pamela Ruth DENISH

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Abstract

The present disclosure relates to microorganisms useful in the biosynthesis of psicose. Also provided are methods of producing the disclosed microorganism and methods of producing psicose.

Claims30

Dependent claims

A recombinant microorganism comprising an exogenous epimerase and an exogenous phosphatase, wherein the recombinant microorganism produces an increased amount of psicose as compared to a naturally occurring microorganism.

Dependencies are inferred from the claim text.

Facts

Application

19/109,749Filed 7 Sep 2023

Priority

9 Sep 2022

Published

19 Mar 2026

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Classification15 codes

C12P 19/24
Preparation of compounds containing saccharide radicals: produced by the action of an isomerase, e.g. fructose
C12N 1/20
Microorganisms; Compositions thereof ; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of…:…
C12N 9/1205
Transferring phosphorus containing groups, e.g. kinases: phosphotransferases with an alcohol group as acceptor , e.g. protein kinases
C12N 9/16
Hydrolases: acting on ester bonds

Abstract

The present disclosure relates to microorganisms useful in the biosynthesis of psicose. Also provided are methods of producing the disclosed microorganism and methods of producing psicose.