Cationic lipids and uses thereof

A method comprising contacting a cell with a composition comprising a compound of Formula (V):

• wherein
• R21, R23, and R24 are independently selected from hydrogen, C1-6 alkyl, C1-6 haloalkyl, C1-6 hydroxyalkyl, C1-6 alkoxyalkyl, C5-10 aryl, 5- to 10-membered heteroaryl, or C3-6 cycloalkyl;
• n is an integer from 1 to 20;
• m is 6, 7, 8, 9, or 10;
• p is 1, 2, 3, or 4;
• q is 1, 2, 3, 4, or 5;
• and
• r is 1, 2, 3, 4, 5, or 6.