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US 2026/0076993 A1Published application
Composition for the treatment of lesions of the respiratory system
AssigneesDenis BARRITAULT, Organes, Tissus: Régénération, Réparation, Remplacement
InventorDenis BARRITAULT
Life of this patent
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Abstract
The present invention relates to a pharmaceutical composition for use in the prophylaxis and/or treatment of lesions of the respiratory system, in particular lung lesions, caused by a microorganism. The present invention also relates to a pharmaceutical composition for use in the treatment of lesions of the respiratory system, in particular lung lesions, caused by a microorganism. The present invention has an application in particular in the therapeutic, pharmaceutical and veterinary fields.
Claims20
A method comprising:
- administering a therapeutically effective amount of a pharmaceutical composition to a patient in need thereof as a prophylaxis and/or treatment of lesions of the respiratory system caused by a microorganism, said pharmaceutical composition comprising:
- a biocompatible polymer of the following general formula (I)
- wherein:
- A is a glucose monomer,
- X is an R1COOR2, —CH2—COO−, or carboxymethyl,
- Y is a R7SO3R8, —SO3−, or —SO3−Na+ wherein:
- R1 is an aliphatic hydrocarbon chain, optionally branched and/or unsaturated, R2 and R8 are independently a hydrogen atom or an M+ cation,
- R7 is a bond,
- a is the number of monomers,
- x is the rate of substitution of the A monomers by X groups,
- y is the rate of substitution of the A monomers by Y groups,
- wherein the microorganism is selected from the group consisting of a virus, a bacterium and a parasite, said virus is selected from the group consisting of a coronavirus, a rhinovirus and an influenzavirus, said bacterium is selected from the group consisting of Streptococcus pneumoniae, Hemophilus influenza type B and a mycoplasma, and said parasite is selected from the group consisting of Trypanosoma cruzi and an amoeba.
9 more elements
A method comprising:
- administering a therapeutically effective amount of a pharmaceutical composition to a patient in need thereof as a treatment of deficiencies of respiratory functions comprising a reduction and/or impairment of the exchange of oxygen (O2) and carbon dioxide (CO2) between the air and the blood due to lung lesions of the respiratory system caused by a microorganism, said pharmaceutical composition comprising:
- a biocompatible polymer of the following general formula (I)
- wherein:
- A is a glucose monomer,
- X is an R1COOR2, —CH2—COO−, or carboxymethyl,
- Y is an R7SO3R8, —SO3, or —SO3-Nat, wherein:
- R1 is an aliphatic hydrocarbon chain, optionally branched and/or unsaturated,
- R2 and R5 are independently a hydrogen atom or an M+ cation,
- R7 is a bond,
- a is the number of monomers,
- x is the rate of substitution of the A monomers by X groups,
- y is the rate of substitution of the A monomers by Y groups,
- wherein the microorganism is selected from the group consisting of a virus, a bacterium and a parasite, said virus is selected from the group consisting of a coronavirus, a rhinovirus and an influenzavirus, said bacterium is selected from the group consisting of Streptococcus pneumoniae, Hemophilus influenza type B and a mycoplasma, and said parasite is selected from the group consisting of Trypanosoma cruzi and an amoeba.
10 more elements
Dependencies are inferred from the claim text.