# US 2026/0076901 A1 · Material for Gel Formation and Gel Composition

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- Number: US 2026/0076901 A1
- Document ID: US20260076901A1
- Status: Published application
- Kind: A1
- Application number: 19/109,105
- Filed: 2023-05-01
- Published: 2026-03-19
- Earliest claimed: 2022-09-07
- Assignees: Kewpie Corporation
- Applicants: Kewpie Corporation
- Inventors: Shunichi Fujikawa
- Web page: https://patentgrep.com/patent/US20260076901A1

## CPC

- A61K 9/0024: {Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue (compositions for intravenous administration, normal injectable solutions or dispersions for, e.g. subcutaneous administration A61K9/0019; brain implants A61K9/0085; (coated) prostheses, catheters or stents A61L)}
- A61K 9/06: Ointments; Bases therefor; {Other semi-solid forms, e.g. creams, sticks, gels (composition of ointments, creams or gels A61K47/00)}
- A61K 31/728: Hyaluronic acid
- A61K 47/36: Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61L 26/0023: {Polysaccharides}
- A61L 26/0066: {Medicaments; Biocides}
- A61L 26/008: {Hydrogels or hydrocolloids}
- A61L 27/20: Polysaccharides
- A61L 27/52: Hydrogels or hydrocolloids
- A61L 27/54: Biologically active materials, e.g. therapeutic substances {(A61L27/227 takes precedence)}
- A61L 31/042: {Polysaccharides}
- A61L 31/145: {Hydrogels or hydrocolloids}
- A61L 31/16: Biologically active materials, e.g. therapeutic substances {(A61L31/047 takes precedence)}
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)

## Abstract

One aspect of the present invention relates to a material for gel formation containing at least one component A selected from the group consisting of a modified hyaluronic acid having a thiol group and a salt thereof, and at least one component B selected from the group consisting of a modified hyaluronic acid having a maleimide group and a salt thereof.

## Claims

### Claim at position 1

1: A material for gel formation, comprising:
at least one component A selected from the group consisting of a modified hyaluronic acid having a thiol group and a salt thereof; and
at least one component B selected from the group consisting of a modified hyaluronic acid having a maleimide group and a salt thereof.

### Claim at position 2 (depends on 1)

2: The material for gel formation according to claim 1, wherein a thiol group modification rate of the component A is 5% or more and 50% or less.

### Claim at position 3 (depends on 1)

3: The material for gel formation according to claim 1, wherein the component A has an average molecular weight of 10,000 or more and 600,000 or less.

### Claim at position 4 (depends on 1)

4: The material for gel formation according to claim 1, wherein a maleimide group modification rate of the component B is 1% or more and 30% or less.

### Claim at position 5

5: A material for in situ gel formation, comprising at least one selected from the group consisting of a modified hyaluronic acid having a thiol group and a salt thereof.

### Claim at position 6

6: A material for in situ gel formation, comprising at least one selected from the group consisting of a modified hyaluronic acid having a maleimide group and a salt thereof.

### Claim at position 7

7: A gel composition, comprising:
at least one component A selected from the group consisting of a modified hyaluronic acid having a thiol group and a salt thereof; and
at least one component B selected from the group consisting of a modified hyaluronic acid having a maleimide group and a salt thereof, wherein
the thiol group and the maleimide group are bonded to each other.