Electro-thermal therapy for the treatment of diseased or unwanted tissue
AssigneeNorth Carolina State University
InventorsMichael Benjamin Sano, Christopher Carl Fesmire
Life of this patent
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Abstract
A method for performing electrothermal therapy (ETT) includes inserting one or more electrodes into a target tissue, inserting one or more temperature sensors into the target tissue, selecting a pulse waveform for a plurality of electrical pulses, and delivering to the target tissue the plurality of electrical pulses having the selected pulse waveform through the one or more electrodes, wherein a delay between ones of the plurality of electrical pulses is selected based on a temperature reading from the one or more temperature sensors.
Claims32
A method of treating tissue cells within a body of a patient, the method comprising:
- modifying or killing target cells of a target tissue with electrical pulses and dynamically adjusting an energy delivery rate of the electrical pulses in response to a temperature measurement of the target tissue,
- wherein dynamically adjusting the energy delivery rate of the electrical pulses comprises increasing or decreasing a delay between successive ones of the electrical pulses in response to the temperature measurement being outside a specified range.
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A method of treating tissue cells within a body of a patient, the method comprising:
- modifying or killing target cells of a target tissue with electrical pulses and dynamically adjusting an energy delivery rate of the electrical pulses in response to an impedance measurement of the target tissue,
- wherein dynamically adjusting the energy delivery rate of the electrical pulses comprises increasing or decreasing a delay between successive ones of the electrical pulses in response to the impedance measurement being outside a specified range.
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A system comprising:
- one or more electrodes configured to deliver electrical pulses to a target tissue of a patient;
- one or more sensors configured to measure at least one of a temperature or an impedance of the target tissue;
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- a computer controller configured to dynamically adjust an energy delivery rate of the electrical pulses in response to at least one of a temperature measurement or an impedance measurement of the target tissue received from the one or more sensors, to thereby modify or kill target cells of the target tissue,
- wherein the computer controller is configured to increase or decrease a delay between successive ones of the electrical pulses in response to the temperature measurement or the impedance measurement being outside a specified range, to thereby dynamically adjust the energy delivery rate of the electrical pulses.
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Dependencies are inferred from the claim text.