# US 2026/0076646 A1 · Left atrial appendage closure device specification from 2d ice to treat atrial fibrillation patients > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2026/0076646 A1 - Document ID: US20260076646A1 - Status: Published application - Kind: A1 - Application number: 18/889,729 - Filed: 2024-09-19 - Published: 2026-03-19 - Earliest claimed: 2024-09-19 - Assignees: Siemens Medical Solutions USA, Inc. - Applicants: Siemens Medical Solutions USA, Inc. - Inventors: Gareth Funka-Lea; Athira Jane Jacob; Paul Klein - Web page: https://patentgrep.com/patent/US20260076646A1 ## CPC - A61B 8/12: in body cavities or body tracts, e.g. by using catheters - A61B 5/0044: {for the heart} - A61B 8/0883: {for diagnosis of the heart} - A61B 8/463: {characterised by displaying multiple images or images and diagnostic data on one display} - A61B 8/466: {adapted to display 3D data} - A61B 8/483: {involving the acquisition of a 3D volume of data} - A61B 8/5223: {for extracting a diagnostic or physiological parameter from medical diagnostic data (for algorithms to analyse biomedical images G06T7/0012)} - A61B 8/5253: {combining overlapping images, e.g. spatial compounding} - A61B 34/10: Computer-aided planning, simulation or modelling of surgical operations - G06N 3/02: Neural networks - G06N 3/045: Combinations of networks - G06N 3/08: Learning methods - G06T 7/10: Segmentation; Edge detection (motion-based segmentation G06T7/215) - G06T 7/38: Registration of image sequences - G06T 7/62: of area, perimeter, diameter or volume - G16H 20/40: relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture - G16H 30/40: for processing medical images, e.g. editing - G16H 50/50: for simulation or modelling of medical disorders - A61B 2034/105: {Modelling of the patient, e.g. for ligaments or bones} - A61B 2034/2051: {Electromagnetic tracking systems} - A61B 2090/3782: {transmitter or receiver in catheter or minimal invasive instrument} - A61B 2576/023: for the heart - G06T 2200/08: involving all processing steps from image acquisition to 3D model generation - G06T 2207/10132: Ultrasound image - G06T 2207/20084: Artificial neural networks [ANN] - G06T 2207/20212: Image combination - G06T 2207/30048: Heart; Cardiac - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - G06N: COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS - G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL - G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA ## Abstract Systems and methods for left atrial appendage closure device specification from two dimensional (2D) Intracardiac Echo imaging (ICE). In an imaging procedure, 2D ICE is used to acquire images of the left atrium of a patient. A model of the left atrium is generated from the images of the left atrium. The model of the left atrium is used to validate subsequent imaging of the left atrial appendage of the patient. Anatomical measurements from the validated subsequent imaging may be used to select or specify a left atrial appendage closure device in order to, for example, treat atrial fibrillation patients. ## Claims ### Claim 1 A method for left atrial appendage assessment, the method comprising: acquiring a plurality of images of a left atrium of a patient; generating a model of the left atrium from the plurality of images of the left atrium; acquiring a plurality of images of a left atrial appendage of the patient; determining, based on the model, if the plurality of images of the left atrial appendage are sufficient to accurately estimate a specification of an appropriate left atrial appendage closure device; and computing and providing, when the plurality of images of the left atrial appendage are sufficient, an anatomical measurement of the left atrial appendage or providing, when the plurality of images are not sufficient, instructions for an operator to acquire additional images of the left atrial appendage. ### Claim 2 (depends on 1) The method of claim 1, further comprising: identifying the appropriate left atrial appendage closure device based on the anatomical measurement of the left atrial appendage. ### Claim 3 (depends on 2) The method of claim 2, further comprising: performing a left atrial appendage closure procedure using the appropriate left atrial appendage closure device. ### Claim 4 (depends on 1) The method of claim 1, wherein acquiring comprises acquiring two dimensional images using an ICE ultrasound imaging system. ### Claim 5 (depends on 1) The method of claim 1, wherein the model comprises a three dimensional segmentation of the left atrium of the patient. ### Claim 6 (depends on 1) The method of claim 1, wherein generating the model comprises: determining positions of scan planes within a cardiac system of the patient for the plurality of images of the left atrium; forming an ICE volume from the plurality of images of the left atrium and the positions; and generating a three-dimensional segmented model from input of the ICE volume to a machine learned network. ### Claim 7 (depends on 6) The method of claim 6, wherein determining if the plurality of images of the left atrial appendage are sufficient comprises: registering one or more of the plurality of images to the three-dimensional segmented model; and checking that a full diameter of a left atrial appendage ostia is present in at least one image of the plurality of images of the left atrial appendage using a position of the at least one image relative to the model. ### Claim 8 (depends on 1) The method of claim 1, wherein determining comprises: providing an uncertainty measurement in the model and in an image frame position to determine an estimate of a probability that a left atrial appendage ostia diameter has been measured to a certain confidence. ### Claim 9 (depends on 1) The method of claim 1, wherein providing further comprises: one or more additional measurements of a size or shape of the left atrial appendage that is used in choosing a device for an left atrial appendage closure. ### Claim 10 (depends on 1) The method of claim 1, wherein the instructions are based on simulated alternative views from the model of the left atrium that a ICE catheter could reach that would allow for an accurate calculation of a left atrial appendage ostia diameter. ### Claim 11 A system for left atrial appendage device selection, the system comprising: a 2D ICE imaging system configured to acquire left atrium image data of a left atrium of a patient and left atrial appendage image data of a left atrial appendage of the patient; and an imaging processor configured to generate a three dimensional model of the left atrium of the patient from the left atrium image data, the imaging processor further configured to register the left atrial appendage image data to the three dimensional model and determine that the left atrial appendage is sufficiently visualized in the left atrial appendage image data; wherein the imaging processor is further configured to compute at least one anatomical measurement of the left atrial appendage and select a device for an left atrial appendage closure procedure based on at the at least one anatomical measurement. ### Claim 12 (depends on 11) The system of claim 11, wherein the left atrium is sufficiently visualized when a left atrial appendage ostia diameter has been measured up to a certain confidence. ### Claim 13 (depends on 11) The system of claim 11, wherein the imaging processor is further configured to determine that the left atrial appendage is not sufficiently visualized in the left atrial appendage image data, wherein the imaging processor is configured to generate instructions to an operator to acquire additional image data of the left atrial appendage. ### Claim 14 (depends on 11) The system of claim 11, wherein the three dimensional model is generated by segmenting and combining a plurality of scan planes from the left atrium image data. ### Claim 15 (depends on 14) The system of claim 14, wherein generating the three dimensional model comprises: determining positions of scan planes within a cardiac system of the patient for the left atrium image data; forming an ICE volume from the scan planes and the positions; and generating a three-dimensional segmented model from input of the ICE volume to a machine learned network. ### Claim 16 (depends on 11) The system of claim 11, further comprising: a display configured to display the left atrium image data, the left atrial appendage image data, and/or the three dimensional model of the left atrium. ### Claim 17 A non-transitory computer implemented storage medium that stores machine-readable instructions executable by at least one processor for left atrial appendage assessment, the machine-readable instructions comprising: acquiring a plurality of images of a left atrium of a patient; generating a model of the left atrium from the plurality of images of the left atrium; acquiring a plurality of images of a left atrial appendage of the patient; determining, based on the model, if the plurality of images of the left atrial appendage are sufficient to accurately estimate a specification of a left atrial appendage closure device; and computing and providing, when the plurality of images of the left atrial appendage are sufficient, an anatomical measurement of the left atrial appendage or providing, when the plurality of images are not sufficient, instructions for an operator to acquire additional images of the left atrial appendage. ### Claim 18 (depends on 17) The non-transitory computer implemented storage medium of claim 17, wherein the instructions for generating the model comprise: determining positions of scan planes within a cardiac system of the patient for the plurality of images of the left atrium; forming an ICE volume from the plurality of images of the left atrium and the positions; and generating a three-dimensional segmented model from input of the ICE volume to a machine learned network. ### Claim 19 (depends on 17) The non-transitory computer implemented storage medium of claim 17, wherein the instructions for determining comprise: registering the plurality of images of the left atrial appendage to the model of the left atrium; and determining if a full view of a diameter of the left atrial appendage is visualized in the plurality of images of the left atrial appendage. ### Claim 20 (depends on 17) The non-transitory computer implemented storage medium of claim 17, wherein acquiring is performed using a 2D ICE imaging system.