Methods, systems, and apparatuses for collecting a high volume of bodily fluid using handheld bodily fluid collection devices

A device for withdrawing bodily fluid from a subject, comprising:

• a housing including a bottom surface configured to be positioned against skin of the subject and an opening extending through the bottom surface;
• a flexible membrane coupled to the housing and extending partially across the opening in the bottom surface;
• a platform coupled to the flexible membrane and positioned at a center of the flexible membrane, wherein the flexible membrane and the platform are configured to be positioned in contact with the skin;
• a collection cartridge removably coupled with the housing;
• a skin-piercing assembly positioned at least partially within the housing and having a skin-piercing feature configured to pierce the skin;
• and
• an actuator operably coupled to the skin-piercing assembly and movable relative to the housing, wherein—
• movement of the actuator toward the opening deploys the skin-piercing feature through the opening and into the skin,
• movement of the actuator away from the opening draws a vacuum within at least a portion of the housing, and
• the vacuum is configured to draw the flexible membrane, the platform, and at least a portion of the skin at least partially through the opening.

A device for withdrawing bodily fluid from a subject, comprising:

• a housing including a bottom surface configured to be positioned against skin of the subject and an opening extending through the bottom surface;
• a flexible membrane coupled to the housing and extending partially across the opening in the bottom surface;
• a platform coupled to the flexible membrane, wherein the platform is rigid, and wherein the flexible membrane and the platform are configured to be positioned in contact with the skin;
• a collection cartridge removably coupled with the housing;
• a skin-piercing assembly positioned at least partially within the housing and having a skin-piercing feature configured to pierce the skin;
• and
• an actuator operably coupled to the skin-piercing assembly and movable relative to the housing, wherein—
• movement of the actuator toward the opening deploys the skin-piercing feature through the opening and into the skin,
• movement of the actuator away from the opening draws a vacuum within at least a portion of the housing, and
• the vacuum is configured to draw the flexible membrane, the platform, and at least a portion of the skin at least partially through the opening.

A device for withdrawing bodily fluid from a subject, comprising:

• a housing including a bottom surface configured to be positioned against skin of the subject and an opening extending through the bottom surface;
• a flexible membrane coupled to the housing and extending partially across the opening in the bottom surface;
• a platform coupled to the flexible membrane, wherein the flexible membrane and the platform are configured to be positioned in contact with the skin;
• a collection cartridge removably coupled with the housing;
• a skin-piercing assembly positioned at least partially within the housing and having a skin-piercing feature configured to pierce the skin;
• and
• an actuator operably coupled to the skin-piercing assembly and movable relative to the housing, wherein—
• movement of the actuator toward the opening deploys the skin-piercing feature through the opening and into the skin,
• movement of the actuator away from the opening draws a vacuum within at least a portion of the housing,
• the vacuum is configured to draw the flexible membrane, the platform, and at least a portion of the skin at least partially through the opening, and
• wherein the platform is configured to control a curvature of the skin to mitigate bruising of the skin of the subject.

A bodily fluid collection system, comprising:

• a handheld housing including:
• a bottom surface in contact with skin of a patient and having an opening,
• a skin-piercing feature configured to form an incision in the skin through the opening,
• a flexible membrane coupled to the bottom surface and extending partially across the opening,
• a vacuum mechanism configured to apply vacuum pressure to the skin through the opening,
• a platform positioned in contact with the skin and coupled to the bottom surface via the flexible membrane, wherein the vacuum pressure is configured to draw the flexible membrane, the platform, and at least a portion of the skin at least partially through the opening, and
• a connector angled relative to the bottom surface, wherein the connector comprises a moveable channel;
• and
• a collection reservoir configured to be fluidly coupled to the connector and to extend at least partially through the moveable channel, wherein the collection reservoir is configured to collect bodily fluid flowing from the incision, and wherein the moveable channel is configured to help position the collection reservoir proximate to the skin.