# US 2026/0076584 A1 · System and method for magnetic occult lesion localization and imaging

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- Number: US 2026/0076584 A1
- Document ID: US20260076584A1
- Status: Published application
- Kind: A1
- Application number: 19/320,993
- Filed: 2025-09-05
- Published: 2026-03-19
- Earliest claimed: 2016-09-09
- Assignees: Stryker Corporation
- Applicants: Stryker Corporation
- Inventors: Ananth RAVI; John DILLON
- Web page: https://patentgrep.com/patent/US20260076584A1

## CPC

- A61B 5/05: Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves (measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24)
- A61B 5/062: {using magnetic field}
- A61B 34/20: Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B 90/00: Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B 90/39: {Markers, e.g. radio-opaque or breast lesions markers}
- A61M 37/0069: {Devices for implanting pellets, e.g. markers or solid medicaments (for introducing of radioactive sources for interstitial radiation therapy, i.e. brachytherapy A61N5/1027)}
- G01R 33/0005: {Geometrical arrangement of magnetic sensor elements; Apparatus combining different magnetic sensor types (G01R33/0206 takes precedence)}
- G01R 33/0047: {Housings or packaging of magnetic sensors (packaging of semiconductor devices H10W99/00); Holders}
- G01R 33/02: Measuring direction or magnitude of magnetic fields or magnetic flux (G01R33/20 takes precedence)
- G01V 3/08: operating with magnetic or electric fields produced or modified by objects or geological structures or by detecting devices (with electromagnetic waves G01V3/12)
- G01V 3/081: {the magnetic field is produced by the objects or geological structures (characterised by the method of magnetic field measurement G01R33/00)}
- G01V 3/12: operating with electromagnetic waves {(operating with millimetre waves G01V8/005)}
- A61B 2034/2051: {Electromagnetic tracking systems}
- A61B 2034/2055: {Optical tracking systems}
- A61B 2034/2063: {Acoustic tracking systems, e.g. using ultrasound}
- A61B 2090/3908: {Soft tissue, e.g. breast tissue}
- A61B 2090/3954: {magnetic, e.g. NMR or MRI}
- A61B 2090/3958: {emitting a signal}
- A61B 2090/3987: {Applicators for implanting markers}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12)
- G01V: GEOPHYSICS; GRAVITATIONAL MEASUREMENTS; DETECTING MASSES OR OBJECTS; TAGS (means for indicating the location of accidentally buried, e.g. snow-buried, persons A63B29/02)

## Abstract

Systems and methods for marking the location and extent of an anatomical region-of-interest, such as a tumor, using magnetic seeds whose position and orientation are measured or otherwise detected using a detection device that includes two or more magnetic sensors are described. One or more magnetic seeds are implanted to mark and define the center and extent of an anatomical region-of-interest and a magnetic sensor-based detector system is used to accurately identify the location of the magnetic seeds.

## Claims

### Claim 1

(canceled)

### Claim 2

A method for localizing a marker, comprising:
generating, by a first magnetic sensor of a detector apparatus and a second magnetic sensor of the detector apparatus, signal data representative of the magnetic field generated by the marker, wherein the first magnetic sensor is proximal to the second magnetic sensor and an operative sensor axis of the first magnetic sensor is not parallel with an operative sensor axis of the second magnetic sensor;
processing, by at least one processor, the signal data generated by the first magnetic sensor and the second magnetic sensor to determine a location of the marker; and
providing an output based on the determined location of the marker.

### Claim 3 (depends on 2)

The method of claim 2, wherein the detector apparatus comprises a housing having a proximal portion and a distal portion, the distal portion being angled with respect to the proximal portion, and wherein the first magnetic sensor is located in the proximal portion and the second magnetic sensor is located in the distal portion.

### Claim 4 (depends on 3)

The method of claim 3, wherein the operative sensor axis of the second magnetic sensor is not parallel with a central axis of the proximal portion, and at least one of the first magnetic sensor and the second magnetic sensor is offset from the central axis of the proximal portion.

### Claim 5 (depends on 2)

The method of claim 2, comprising detecting the marker outside of a viewing window of the detector apparatus and providing the output only when the marker is determined to be within the viewing window.

### Claim 6 (depends on 2)

The method of claim 2, wherein the detector apparatus comprises the first magnetic sensor and the second magnetic sensor and no other sensors.

### Claim 7 (depends on 2)

The method of claim 2, comprising tracking the detector apparatus by a navigation system.

### Claim 8 (depends on 2)

The method of claim 2, wherein processing the signal data includes accounting for an anisotropic geometry of the magnetic field generated by the marker.

### Claim 9

An apparatus for localizing a marker, comprising:
a first magnetic sensor; and
a second magnetic sensor located distally of the first magnetic sensor, wherein an operative sensor axis of the second magnetic sensor is non-parallel with an operative sensor axis of the first magnetic sensor, wherein the first magnetic sensor and the second magnetic sensor are configured to detect the magnetic field generated by the marker and in response thereto generate signal data representative of the magnetic field.

### Claim 10 (depends on 9)

The apparatus of claim 9, comprising at least one processor in communication with the first magnetic sensor and the second magnetic sensor and configured to receive the signal data therefrom and to process the signal data to determine a location of the marker.

### Claim 11 (depends on 10)

The apparatus of claim 10, comprising an output device in communication with the at least one processor and configured to provide feedback to a user based on the determined location of the marker.

### Claim 12 (depends on 11)

The apparatus of claim 11, wherein the at least one processor is configured to control the output device to provide the feedback to the user only when the marker is located within a predefined volume regardless of whether the marker is detected outside of the predefined volume.

### Claim 13 (depends on 10)

The apparatus of claim 10, comprising a display, wherein the at least one processor is configured to determine an error in the location of the marker and display the error via the display.

### Claim 14 (depends on 13)

The apparatus of claim 13, wherein the output device is configured to provide at least one of a visual feedback to the user or an auditory feedback to the user.

### Claim 15 (depends on 13)

The apparatus of claim 13, wherein the at least one processor is configured to provide one or more numerical values associated with the location of the marker relative to the apparatus via the output device.

### Claim 16 (depends on 13)

The apparatus of claim 13, wherein the output device comprises a display and the at least one processor is configured to display the location of the marker via the display.

### Claim 17 (depends on 10)

The apparatus of claim 10, wherein the at least one processor is configured to account for anisotropic geometry of the magnetic field generated by the marker.

### Claim 18 (depends on 9)

The apparatus of claim 9, comprising a housing having a proximal portion and a distal portion, the distal portion being angled with respect to the proximal portion, and wherein the first magnetic sensor is located in the proximal portion and the second magnetic sensor is located in the distal portion.

### Claim 19 (depends on 18)

The apparatus of claim 18, wherein the operative sensor axis of the second magnetic sensor is not parallel with a central axis of the proximal portion, and at least one of the first magnetic sensor and the second magnetic sensor is offset from the central axis of the proximal portion.

### Claim 20

A kit for localization of an implantable marker, comprising:
a detector apparatus comprising:
a first magnetic sensor, and
a second magnetic sensor located distally of the first magnetic sensor, wherein an operative sensor axis of the second magnetic sensor is non-parallel with an operative sensor axis of the first magnetic sensor,
wherein the first magnetic sensor and the second magnetic sensor are configured to detect a magnetic field associated with the marker and in response thereto generate signal data representative of the magnetic field.

### Claim 21 (depends on 20)

The kit of claim 20, comprising the marker and an introducer for implanting the marker.
