Cell culture media specification attribute assessment

A computer-implemented method comprising:

• obtaining respective impurity levels of at least one impurity in each raw material of a plurality of raw materials;
• obtaining a formulation of a cell culture medium, wherein the formulation) indicates a ratio of the plurality of raw materials in the cell culture medium;
• determining, at least partially based on the formulation and on the respective impurity levels, a total impurity level of the at least one impurity in the cell culture medium;
• and
• determining, at least partially based on the formulation, on the respective impurity levels in each raw material of the plurality of raw materials and on at least one predefined criterion for the total impurity level, a respective allowable range of the impurity level of the at least one impurity in at least one raw material of the plurality of raw materials, such that under variation of the respective impurity level of the at least one impurity in at least one raw material within the allowable range, the total impurity level of the at least one impurity in the cell culture medium still meets the predefined criterion for the total impurity.