Rotary perfusion device for culturing biological cells

A perfusion vessel comprising:

• a body extending between a first end and a second end and being configured to be rotated about an axis of rotation, the body including one or more helical conduits configured to receive a fluid and extending between the first end and the second end of the body along an exterior surface of the body, the body defining a reservoir configured to receive the fluid and extending between the first end and the second end of the body, and the body defining a first aperture and a second aperture each in communication with the one or more helical conduits and the reservoir and configured for passage of the fluid;
• and
• optionally a support extending between a first end and a second end, the support being received within the reservoir of the body, the support including a plurality of wells configured to accommodate biological cells and a permeable membrane disposed below the plurality of wells;
• wherein the helical conduit of the body is configured to facilitate movement of the fluid between the first aperture and the second aperture of the body during rotation of the body.