Back to results
US 2026/0070908 A1Published application
Novel functionalized lactams as modulators of the 5-hydroxytryptamine receptor 7 and their method of use
AssigneesTemple University of the Commonwealth System of Higher Education, Praevenfix, LLC
InventorsDaniel J. Canney, Benjamin E. Blass, Kevin M. Blattner, Douglas A. Pippin
Life of this patent
Estimating the term…
Abstract
Pharmaceutical compositions of the invention comprise functionalized lactam derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
Claims24
A compound of Formula (XXII):
- wherein:
- n is 2,
- R3 is 4-F-phenyl, and
- R7 is COMe.
- or a pharmaceutically acceptable salt or enantiomer thereof.
2 more elements
A compound of Formula (XXII):
- wherein:
- n is 2,
- R3 is 4-F-phenyl, and
- R7 is CO2Me.
- or a pharmaceutically acceptable salt or enantiomer thereof.
2 more elements
A compound of Formula (XXII):
- wherein:
- n is 2,
- R3 is 4-F-phenyl, and
- R7 is CO2tBu.
- or a pharmaceutically acceptable salt or enantiomer thereof.
2 more elements
A compound of Formula (XXII):
- wherein:
- n is 2,
- R3 is 4-Cl-phenyl, and
- R7 is COMe.
- or a pharmaceutically acceptable salt or enantiomer thereof.
2 more elements
Dependencies are inferred from the claim text.