Composition for fluorescent labeling, fluorescent probe, injection agent, syringe filling, medical apparatus, medical fiber material, method for producing composition for fluorescent labeling, and method for producing medical fiber material
AssigneesVita Corporation, National University Corporation Kobe University
InventorsShinobu TSUCHIDA, Takeshi URADE
Life of this patent
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Abstract
A composition for fluorescent labeling comprises a compound (A) that is an ICG compound and a hydroxyl group-containing organic compound (B). In this way, it is possible to provide a composition for fluorescent labeling that has excellent compartment identifiability to identify an observation target more accurately, a long light emission time to observe the observation target for a long time, a small load to a biological body, and good economic efficiency.
Claims15
1-25. (canceled)
A composition for fluorescent labeling, comprising:
- a compound (A) expressed by the following formula (1);
- a hydroxyl group-containing organic compound (B);
- and
- a resin (C) comprising at least one selected from a group consisting of polyurethane resin, olefin resin, epoxy resin, vinyl chloride resin, fluorocarbon resin, polycarbonate resin, polyamide resin, ABS resin, acetal resin, acrylic resin, and silicone resin.
- where, R1 and R2 independently represent hydrogen, an alkyl group of carbon number 1 to 13, an alkoxy group of carbon number 1 to 13, or a sulfonate group, p represents an integer of 1 to 5, and m and n independently represent an integer of 1 to 12.
An injection agent for labeling an object existing on mucous membrane or skin, comprising:
- a compound (A) expressed by the following formula (1);
- a hydroxyl group-containing organic compound (B);
- and
- a component (D) as an additive.
- where, R1 and R2 independently represent hydrogen, an alkyl group of carbon number 1 to 13, an alkoxy group of carbon number 1 to 13, or a sulfonate group, p represents an integer of 1 to 5, and m and n independently represent an integer of 1 to 12.
A method for producing a medical fiber material, the method comprising:
- an impregnation step of impregnating or spraying a fiber material comprising a hydroxyl group-containing organic compound (B) with a solution comprising 0.0000001 to 10 wt % of a compound (A) expressed by the following formula (1);
- and
- a shielding step of shielding light when the impregnation step is performed.
- where, R1 and R2 independently represent hydrogen, an alkyl group of carbon number 1 to 13, an alkoxy group of carbon number 1 to 13, or a sulfonate group, p represents an integer of 1 to 5, and m and n independently represent an integer of 1 to 12.
Dependencies are inferred from the claim text.