Nanoparticle-derived vaccines against poxviruses, and methods for making and using the same

Abstract

The present disclosure relates generally to vaccines against orthopoxviruses, and methods for making and using such vaccines. In particular, in some embodiments, the present disclosure relates to nanoparticle-derived vaccines, and compositions based thereon, that elicit an immune response against an orthopoxvirus. The present disclosure further relates to the use of vaccines and vaccine compositions for preventing; decreasing the severity, morbidity and/or mortality of; shortening the duration of; and/or reducing the symptoms of, a poxvirus infection, such as, for example, an orthopoxvirus infection.

Dependencies are inferred from the claim text.