Pharmaceutical compositions comprising poh derivatives
AssigneeUniversity of Southern California
InventorsThomas CHEN, Daniel LEVIN, Satish PUPPALI
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Abstract
The present invention provides for a derivative of monoterpene or sesquiterpene, such as a perillyl alcohol derivative. For example, the perillyl alcohol derivative may be a perillyl alcohol carbamate. The perillyl alcohol derivative may be perillyl alcohol conjugated with a therapeutic agent such as a chemotherapeutic agent. The present invention also provides for a method of treating a disease such as cancer, comprising the step of delivering to a patient a therapeutically effective amount of a derivative of monoterpene (or sesquiterpene). The route of administration may vary, and can include, inhalation, intranasal, oral, transdermal, intravenous, subcutaneous or intramuscular injection.
Claims6
A method for treating glioblastoma in a mammal, comprising delivering to the mammal a therapeutically effective amount of butyryl-POH.
A method for inhibiting or decreasing growth of glioma cells, the method comprising contacting the glioma cells with an effective amount of a butyryl-POH.
Dependencies are inferred from the claim text.