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US 2026/0062374 A1Published application
Process for the preparation of a benzene derivative
OwnerXavier MANIERE, Stefano BERNAinventors
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Abstract
The present invention relates to a process for the preparation of N-[(Z)-3-(3-chloro-4-cyclohexylphenyl)prop-2-enyl]-N-ethylcyclohexanamine or a salt thereof of the following formula (II).
Claims15
A process for the preparation of N-[(Z)-3-(3-chloro-4-cyclohexylphenyl)prop-2-enyl]-N-ethylcyclohexanamine or a salt thereof of the following formula (II):
- characterized in that it comprises a step (i) of reacting a compound of the following formula (1):
- wherein X represents a chloride, a bromide, an iodine, a triflate or an acetyloxy group, with an organozinc compound of the following formula (2):
- wherein X′ represents a chloride, a bromide, or an iodine group, to form the 3-chloro-4-cyclohexylbenzaldehyde of the following formula (I):
Dependencies are inferred from the claim text.