# US 2026/0061174 A1 · Applicator for a microneedle array patch delivery system > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2026/0061174 A1 - Document ID: US20260061174A1 - Status: Published application - Kind: A1 - Application number: 19/320,152 - Filed: 2025-09-05 - Published: 2026-03-05 - Earliest claimed: 2023-06-23 - Assignees: Vaxess Technologies, Inc. - Applicants: Vaxess Technologies, Inc. - Inventors: Matthew Vargas; John Spiridigliozzi; Harrison Wostein; Michael Isidoro; Logan McElhinney - Web page: https://patentgrep.com/patent/US20260061174A1 ## CPC - A61M 37/0015: {by using microneedles} - A61M 2037/0023: {Drug applicators using microneedles} - A61M 2202/0007: introduced into the body - A61M 2205/0216: Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking - A61M 2210/04: Skin - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract An applicator for applying a medicament patch to a subject can include a top portion configured to be pressed downwards to activate an activation mechanism; a bottom portion configured to hold the medicament patch; a middle portion connected to the top portion and the bottom portion, the middle portion comprising a plurality of flex arms configured to contribute about 6-15 lbs to an activation force of the activation mechanism; a piston portion connected to the middle portion; and a compressible member positioned between the middle portion and the piston portion. When the activation mechanism is activated, the piston portion is released from the top portion and the middle portion and moves downwards via force applied by the compressible member. When the piston portion moves downwards, the medicament patch is released from the bottom portion and pushed downward by the piston portion onto a skin surface of the subject. ## Claims ### Claim at position 1 1-20. (canceled) ### Claim 21 An applicator for applying a medicament patch to a subject comprising: a top portion configured to be pressed downwards to activate an activation mechanism; a bottom portion holding the medicament patch such that the medicament patch is suspended above a skin surface of the subject; a middle portion connected to the top portion and the bottom portion, the middle portion comprising one or more elastic members configured to contribute about 6-15 lbs to an activation force of the activation mechanism; a piston portion connected to the middle portion; and a compressible member positioned between the middle portion and the piston portion; wherein when the activation mechanism is activated, the piston portion is released from the top portion and the middle portion and moves downwards via force applied by the compressible member; wherein, when the piston portion moves downwards, the medicament patch is released from the bottom portion and pushed downward by the piston portion directly contacting the medicament patch onto the skin surface of the subject. ### Claim 22 (depends on 21) The applicator of claim 21, wherein the piston portion comprises a dome-shaped face that impacts and pushes the medicament patch downward. ### Claim 23 (depends on 22) The applicator of claim 22, wherein the dome-shaped face comprises a dome radius of about 20-60 mm. ### Claim 24 (depends on 21) The applicator of claim 21, wherein the bottom portion holds the medicament patch via one or more elastic members, each configured to flex outward to release the medicament patch. ### Claim 25 (depends on 24) The applicator of claim 24, wherein the one or more elastic members flex outwardly to release the medicament patch as the piston contacts the medicament patch. ### Claim 26 (depends on 21) The applicator of claim 21, wherein the applicator is configured to push the piston with an impact energy of about 0.3 mJ to 5 mJ per microneedle. ### Claim 27 (depends on 21) The applicator of claim 21, wherein: the middle portion comprises a plurality of zip-tie flexures; the piston portion comprises an arm contacting each of the plurality of zip-tie flexures prior to activation; and wherein, after the piston portion is released and has traveled downward, the arm separates from the plurality of zip-tie flexures, causing the plurality of zip-tie flexures to contact the top portion. ### Claim 28 An applicator for applying a medicament patch to a subject comprising: a top portion configured to be pressed downwards to activate an activation mechanism; a bottom portion holding the medicament patch such that the medicament patch is suspended above a skin surface of the subject; a middle portion connected to the top portion and the bottom portion; a piston portion connected to the top portion and the middle portion and comprising a domed-piston face comprising a dome radius of at least about 20 mm; and a compressible member positioned between the middle portion and the piston portion; wherein when the activation mechanism is activated, the piston portion is released from the top portion and the middle portion and moves downwards via force applied by the compressible member; wherein, when the piston portion moves downwards, the medicament patch is released from the bottom portion and pushed downward by the piston portion directly contacting the medicament patch onto the skin surface of the subject. ### Claim 29 (depends on 28) The applicator of claim 28, wherein the bottom portion holds the medicament patch via a plurality of flex arms, each configured to flex outward to release the medicament patch. ### Claim 30 (depends on 29) The applicator of claim 29, wherein the plurality of flex arms flex outwardly to release the medicament patch as the piston contacts the medicament patch. ### Claim 31 (depends on 28) The applicator of claim 28, wherein the applicator is configured to push the piston with an impact energy of about 0.3 mJ to 5 mJ per microneedle. ### Claim 32 (depends on 28) The applicator of claim 28, wherein: the middle portion comprises a plurality of zip-tie flexures; the piston portion comprises an arm contacting each of the plurality of zip-tie flexures prior to activation; and wherein, after the piston portion is released and has traveled downward, the arm separates from the plurality of zip-tie flexures, causing the plurality of zip-tie flexures to contact the top portion. ### Claim 33 (depends on 28) The applicator of claim 28, wherein the activation mechanism is not pressable when the applicator is in a locked state, and the activation mechanism is pressable when the applicator is in an unlocked state.