# US 2026/0061133 A1 · Administration device for administration of a fluid

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- Number: US 2026/0061133 A1
- Document ID: US20260061133A1
- Status: Published application
- Kind: A1
- Application number: 19/386,687
- Filed: 2025-11-12
- Published: 2026-03-05
- Earliest claimed: 2019-04-18
- Assignees: Boehringer Ingelheim International GmbH
- Applicants: Boehringer Ingelheim International GmbH
- Inventors: Axel ROTH; Viola K. HOLMAN; Hans Jørgen JENSEN
- Web page: https://patentgrep.com/patent/US20260061133A1

## CPC

- A61M 5/28: Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M 5/3146: {Priming, e.g. purging, reducing backlash or clearance}
- A61F 9/0008: {Introducing ophthalmic products into the ocular cavity or retaining products therein (putting in contact lenses A61F9/0061; introducing or retaining media in cavities of the body in general A61M31/00)}
- A61M 5/3135: {characterised by constructional features of the proximal end}
- A61M 5/315: Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod {or piston}; Appliances on the rod for facilitating dosing {; Dosing mechanisms}
- A61M 5/31511: {Piston or piston-rod constructions, e.g. connection of piston with piston-rod (A61M5/5066 takes precedence)}
- A61M 5/31535: {Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose}
- A61M 5/31571: {Means preventing accidental administration (for automatic syringes A61M5/20)}
- A61M 5/3158: {the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button}
- A61M 5/31585: {the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button}
- A61M 5/3204: {Needle cap removers, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices}
- A61M 5/31501: {Means for blocking or restricting the movement of the rod or piston (A61M5/5013 takes precedence)}
- A61M 2005/3152: {including gearings to multiply or attenuate the piston displacing force}
- A61M 2205/276: preventing unwanted use
- A61M 2210/0612: Eyes
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)

## Abstract

An administration device for in particular intravitreal administration of a fluid, the administration device having a preferably pre-filled syringe and an actuation mechanism for actuating the syringe. The administration device preferably includes a priming device, in particular in addition to the actuation mechanism. It is preferably prevented that the priming device be advanced beyond a defined end position. The syringe can preferably be moved within a housing of the administration device and/or positioned completely inside the housing.

## Claims

### Claim 1

An intravitreal administration device for intravitreal administration of a fluid, the administration device comprising a housing, a syringe with a syringe body and a piston and an actuation mechanism for actuating the syringe,
wherein the administration device comprises a priming device configured to act on a the piston of the syringe and a blocking device for preventing the priming device from moving the piston to an end of the syringe,
wherein the housing comprises two housing parts which are moveable relative to at least one of each other and the syringe, and
wherein the actuation mechanism is configured for moving the syringe relative to the housing and comprises a spring for moving the syringe and the housing or a part thereof relative to each other, wherein the spring is at least one of arranged between the two housing parts and configured to move the housing parts apart.

### Claim 2 (depends on 1)

The intravitreal administration device according to claim 1, wherein the priming device is separate from the actuation mechanism and is configured to move or push the piston towards at least one of an outlet of the syringe and relative to the syringe body.

### Claim 3 (depends on 1)

The intravitreal administration device according to claim 1, wherein the priming device comprises an actuation section which is arranged outside the housing.

### Claim 4 (depends on 1)

The intravitreal administration device according to claim 1, wherein the blocking device at least one of projects from an inner wall of the housing and forms an elevation of or on said inner wall.

### Claim 5 (depends on 1)

The intravitreal administration device according to claim 1, wherein the actuation mechanism comprises a pushing element configured for actuating the piston.

### Claim 6 (depends on 1)

The intravitreal administration device according to claim 1, wherein the actuation mechanism comprises an actuation element, which is configured to be actuated in a direction transverse to at least one of a longitudinal extension of the syringe and a direction of movement of the priming device.

### Claim 7 (depends on 1)

The intravitreal administration device according to claim 1, wherein the actuation mechanism comprises an actuation element, which is arranged at least one of laterally at the housing and close to an axial end of the administration device which is opposite to an axial end comprising the priming device or an actuation section thereof of the priming device.

### Claim 8

An intravitreal administration device for intravitreal administration of a fluid, the administration device comprising a housing, a syringe and an actuation mechanism for actuating the syringe,
wherein the actuation mechanism is configured for moving the syringe relative to the housing.

### Claim 9 (depends on 8)

The intravitreal administration device according to claim 8, wherein the actuation mechanism is configured for actuating the syringe by moving a piston of the syringe subsequent to moving the syringe into an administration position.

### Claim 10 (depends on 8)

The intravitreal administration device according to claim 8, wherein the actuation mechanism is configured for positioning at least one of the syringe and an injection needle attached thereto completely inside the housing subsequent to actuating the syringe.

### Claim 11 (depends on 8)

The intravitreal administration device according to claim 8, wherein the actuation mechanism comprises a spring for moving the syringe and the housing or a part thereof relative to each other.

### Claim 12 (depends on 8)

The intravitreal administration device according to claim 8, wherein the actuation mechanism comprises a pushing element for actuating a piston of the syringe, the pushing element comprising a coupling device for coupling to a body of the syringe.

### Claim 13 (depends on 8)

The intravitreal administration device according to claim 8, wherein the housing comprises two housing parts which are moveable relative to at least one of each other and the syringe.

### Claim 14 (depends on 13)

The intravitreal administration device according to claim 13, wherein a spring is at least one of arranged between the two housing parts and configured to move the housing parts apart.

### Claim 15 (depends on 13)

The intravitreal administration device according to claim 13, wherein the administration device is configured so that during actuation of a piston of the syringe, a first one of the housing parts moves relative to the syringe body and a second one of the housing parts, while the syringe body and the first housing part are not moved relative to each other.

### Claim 16 (depends on 8)

Administration device according to claim 8, wherein the actuation mechanism comprises a transmission for moving or retracting the syringe.

### Claim 17 (depends on 8)

The intravitreal administration device according to claim 8, wherein the administration device comprises an alignment device configured to align the administration device to an eye of a patient, the alignment device comprising an alignment area configured for direct contact with an eye of a patient.

### Claim 18 (depends on 17)

The intravitreal administration device according to claim 17, wherein the alignment area is at least one of at least substantially laminar or curved.

### Claim 19 (depends on 17)

The intravitreal administration device according to claim 17, wherein the housing or a part thereof comprises or forms the alignment device.

### Claim 20

A method of intravitreal injection or injection of a fluid or a medicament directly into an eye using an administration device comprising a syringe and an actuation mechanism for actuating the syringe, wherein the administration device comprises a priming device configured to act on a piston of the syringe and a blocking device for preventing the priming device from moving the piston to an end of the syringe,
wherein the housing comprises two housing parts which are moveable relative to at least one of each other and the syringe, and
wherein the actuation mechanism is configured for moving the syringe relative to the housing and comprises a spring for moving the syringe and the housing or a part thereof relative to each other, wherein the spring is at least one of arranged between the two housing parts and configured to move the housing parts apart.

### Claim 21 (depends on 1)

The intravitreal administration device according to claim 1, wherein the syringe comprises a syringe body and a piston and wherein the administration device comprises a the housing surrounding or enclosing at least a major part of the syringe body, wherein the blocking device forms a stop for the priming device, and wherein te the priming device comprises an actuation section which is arranged on an axial end of the administration device and outside the housing so that the actuation section can be actuated by a user.
