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AssigneesHlb Genex, Inc., Biomlogic, Inc., The Asan Foundation, University of Ulsan Foundation for Industry Cooperation
InventorsJae Gu PAN, Eui Joong KIM, Jeong Hyun KIM, In Ik CHANG, Sei Won LEE
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The present invention relates to a composition for the prevention, alleviation, or treatment of fibrotic diseases, containing a Bacillus species strain, a Bacillus species strain spore, each expressing superoxide dismutase, and/or superoxide dismutase. When orally administered, the composition allows the polypeptide with superoxide dismutase activity to remove reactive oxygen species in vivo, thus being helpful for the prevention, improvement, or treatment of fibrotic diseases such as pulmonary fibrosis or hepatic fibrosis.
A composition for treating, ameliorating or preventing a fibrotic disease, comprising, as an active ingredient, at least one selected from the group consisting of a Bacillus sp. strain, a Bacillus sp. strain spore, and a polypeptide having superoxide dismutase (SOD) activity.
Dependencies are inferred from the claim text.