Peptide particles and methods of formation
AssigneeElektrofi, Inc.
InventorsLyndon Fitzgerald Charles, Chase Spenser Coffman, Daniel Benjamin Dadon, Chaitanya Sudrik
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Abstract
The present disclosure relates to compositions and methods that enable the formation of pharmaceutically relevant particles that can be used for therapy. In particular, the methods disclosed herein allow the controlled formation of circular particles comprising biologically active peptides.
Claims25
A particle comprising a peptide, wherein the particle comprises up to about 10% (w/w) of peptide and the circularity of the particle is from about 0.80 to about 1.00.
-17. (canceled)
-28. (canceled)
-41. (canceled)
A composition comprising a plurality of particles, each particle comprising a peptide suspended in a liquid, wherein the particles comprise up to about 10% (w/w) of peptide and the circularity of the particles is from about 0.80 to about 1.00.
-123. (canceled)
A method of forming particles, the method comprising:
- a) providing droplets comprising a first liquid and a peptide;
- b) contacting the droplets comprising the peptide with a second liquid;
- c) allowing the droplets to dry;
- and
- d) removing the first and second liquids,
- thereby forming particles comprising a peptide, wherein the particles comprise up to about 10% (w/w) of peptide and the circularity of the particles is from about 0.80 to about 1.00 after removing the first and second liquids.
-219. (canceled)
Dependencies are inferred from the claim text.