US 2026/0060744 A1 · TREATMENT OF THE REPRODUCTIVE TRACT WITH PULSED ELECTRIC FIELDS

Abstract

Devices, systems and methods are provided for treating conditions of the reproductive tract. A number of conditions can afflict the lining and cell layers deeper within the anatomical structures. For example, cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is a condition involving abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer in situ (CIS). Other conditions include human papillomavirus (HPV)-related cervical disease, various endometrial diseases, acute and chronic cervicitis, and various infections (e.g. trichomoniasis) to name a few. In some embodiments, treatments eliminate diseased, damaged, abnormal or otherwise undesired cells leaving the tissue framework intact. This allows the tissue to regenerate in a normal fashion, avoiding the formation of scar tissue. When the tissue framework is left intact, the framework structure repopulates with healthy cells, regenerating the normal tissue without altering the structural properties.

Claims20

Dependent claims

A system for treating an area of tissue suffering from dysplasia or cancer within a reproductive system of a patient, the system comprising:

an elongate shaft and an energy delivery body disposed near a distal end of the elongate shaft, wherein the elongate shaft is configured to be advanced into the reproductive system so as to position the energy delivery body near or against the area of tissue suffering from dysplasia or cancer within the reproductive system;
and
a generator configured to be electrically coupled to the energy delivery body, wherein the generator includes at least one energy delivery algorithm configured to provide an electric signal of pulsed electric field energy, wherein the pulsed electric field energy comprises a series of biphasic pulses configured to be delivered in packets by the energy delivery body so as to treat the area of tissue suffering from dysplasia or cancer up to a depth of 10 mm from the energy delivery body, wherein the energy comprises non-thermal energy and treating the area of tissue suffering from dysplasia or cancer comprises destroying at least a portion of cells suffering from dysplasia or cancer within the area of tissue while maintaining its collagen structure.

Dependencies are inferred from the claim text.

Treatment of the reproductive tract with pulsed electric fields

Life of this patent

Treatment of the reproductive tract with pulsed electric fields

Life of this patent

Abstract

Claims20