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US 2026/0055367 A1Published application
Methods of making, expanding and purifying midbrain dopaminergic progenitor cells
AssigneeBrainXell, Inc.
InventorZhong-Wei DU
Life of this patent
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Abstract
The present invention provides methods of producing, purifying and expanding mDA progenitor cells.
Claims23
1-72. (canceled)
An in vitro method for inducing differentiation of human stem cells into a midbrain dopamine (mDA) progenitor cell population comprising contacting a suspension of pluripotent stem cells with a BMP inhibitor, a GSK3 inhibitor, a SHH agonist, and a Nodal/Activin inhibitor for about 7 consecutive days to about 12 consecutive days to produce a midbrain floor plate progenitor cell population.
Dependencies are inferred from the claim text.