US 2026/0055085 A1 · HYDROQUINAZOLINE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER

Hydroquinazoline derivatives for the treatment of a disease or disorder

AssigneeNovartis AG

InventorsDaniela ANGST, Philippe Bolduc, Matthew William Carson, Atwood Kim CHEUNG, Véronique Darsigny, Xiang GAO, Viktor HORNAK, Keith JENDZA, Rajesh KARKI, Ajay Kumar LAL, Gang LIU, Justin Yik Ching MAO, Jeffrey M. McKENNA, Erik MEREDITH, Muneto MOGI, Vivek RAUNIYAR, Liansheng SU, Ritesh TICHKULE, Shuangxi WANG, Chun ZHANG, Liang ZHAO, Rui ZHENG

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Abstract

The disclosure relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof wherein A, Ra to Rd, and R4 to R7, are as described herein, as well as compositions and methods of using such compounds.

Claims5

Dependent claims

(canceled)

Dependencies are inferred from the claim text.

Facts

Application

19/091,170Filed 26 Mar 2025

Priority

1 Mar 2023

Published

26 Feb 2026

Term ends

Not estimatedThe source records don’t support an estimate.

Classification20 codes

C07D 403/14
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group…
A61K 31/517
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim: ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A61K 31/55
Having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins: having seven-membered rings, e.g. azelastine, pentylenetetrazole
A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…

Family

Application63/487,756Us provisional application · filed 1 Mar 2023

Application63/550,180Us provisional application · filed 6 Feb 2024

Application18/589,841Continuation · filed 28 Feb 2024

Application18/797,987Continuation · filed 8 Aug 2024

Application19/091,170Continuation

US 12,129,246 B1Related patent

US 2024/0336598 A1Published application

US 2026/0055085 A1This patent

From the US filing history. Foreign family members aren’t listed.