# US 2026/0054043 A1 · Method and apparatus for medical injection

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- Number: US 2026/0054043 A1
- Document ID: US20260054043A1
- Status: Published application
- Kind: A1
- Application number: 18/840,935
- Filed: 2023-08-13
- Published: 2026-02-26
- Earliest claimed: 2023-08-13
- Assignees: Bovonex Inc.
- Applicants: Bovonex Inc.
- Inventors: Ali POORKHALIL; Vahid SAHIHOLNASAB; Mehdi OMIDBAKHSH; Hasan FARROKHZAD
- Web page: https://patentgrep.com/patent/US20260054043A1

## CPC

- A61M 5/3298: {Needles arranged in parallel}
- A61M 37/0015: {by using microneedles}
- A61M 5/19: having more than one chamber
- A61M 39/22: Valves or arrangement of valves {(A61M39/02, A61M39/0247, A61M39/16 take precedence; regulating valves in infusion systems A61M5/16881; in devices worn by the patient for the reception of urine, faeces, catamenial or other discharge, or in colostomy devices A61F5/4405)}
- A61M 5/16827: {controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths (infusion of multiple fluids without using a controller A61M5/1407)}
- A61M 2037/0023: {Drug applicators using microneedles}
- A61M 2037/003: {having a lumen}
- A61M 2037/0061: {Methods for using microneedles}
- A61M 2039/0027: {for mixing several substances from different containers}
- A61M 2202/0007: introduced into the body
- A61M 2202/049: Toxic
- A61M 2205/0216: Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
- A61M 2210/04: Skin
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A medical injection apparatus includes a first reservoir, a second reservoir, a static mixer, and an injection unit. The first reservoir contains a saline solution. The second reservoir contains medicine. The static mixer receives the saline solution from the first reservoir, receives the medicine from the second reservoir, and obtains a medical solution by mixing the medicine with the saline solution. The injection unit receives the medical solution from the static mixer and injects the medical solution into a skin of a subject.

## Claims

### Claim 1

A medical injection apparatus, comprising:
a first reservoir configured to contain a saline solution;
a second reservoir configured to contain medicine;
a static mixer configured to:
receive the saline solution from the first reservoir;
receive the medicine from the second reservoir; and
obtain a medical solution by mixing the medicine with the saline solution; and
an injection unit configured to:
receive the medical solution from the static mixer; and
inject the medical solution into a skin of a subject.

### Claim 2 (depends on 1)

The medical injection apparatus of claim 1, wherein the first reservoir is coupled in parallel with the second reservoir.

### Claim 3 (depends on 2)

The medical injection apparatus of claim 2, further comprising a valve connected between the first reservoir, the second reservoir, and the static mixer, the valve configured to:
seal each of the first reservoir, the second reservoir, and the static mixer with respect to one another responsive to the valve being closed; and
pass the saline solution from the first reservoir and pass the medicine from the second reservoir to the static mixer responsive to the valve being opened.

### Claim 4 (depends on 3)

The medical injection apparatus of claim 3, wherein the medicine comprises a liquid medicine.

### Claim 5 (depends on 4)

The medical injection apparatus of claim 4, wherein the liquid medicine comprises a solution of botulinum toxin.

### Claim 6 (depends on 1)

The medical injection apparatus of claim 1, wherein:
the first reservoir is mounted on the second reservoir; and
the second reservoir is mounted on the static mixer.

### Claim 7 (depends on 6)

The medical injection apparatus of claim 6, wherein:
the first reservoir comprises an elastic balloon; and
the medical injection apparatus further comprises one of a barrier or a semipermeable membrane placed between the elastic balloon and the second reservoir, each of the barrier and the semipermeable membrane configured to pass the saline solution from the elastic balloon to the second reservoir responsive to pressing the elastic balloon.

### Claim 8 (depends on 6)

The medical injection apparatus of claim 6, further comprising a valve connected between the first reservoir and the second reservoir, the valve configured to:
seal the first reservoir with respect to the second reservoir responsive to the valve being closed; and
push the medicine from the second reservoir to the static mixer by passing the saline solution from the first reservoir to the second reservoir responsive to the valve being opened.

### Claim 9 (depends on 8)

The medical injection apparatus of claim 8, wherein the medicine comprises a botulinum toxin powder.

### Claim 10 (depends on 1)

The medical injection apparatus of claim 1, wherein the injection unit comprises:
one or more chambers;
a primary pipe connected to the static mixer;
one or more secondary pipes connecting the primary pipe to the one or more chambers, each respective secondary pipe of the one or more secondary pipes configured to:
receive the medical solution from the static mixer through the primary pipe; and
pass the medical solution to a respective chamber of the one or more chambers; and
a plurality of microneedle arrays attached to the one or more chambers, a tip of each respective microneedle in each respective microneedle array of the plurality of microneedle arrays extruding from a surface of each respective chamber of the one or more chambers.

### Claim 11 (depends on 10)

The medical injection apparatus of claim 10, wherein each of the plurality of microneedle arrays comprises an array of hollow microneedles.

### Claim 12 (depends on 10)

The medical injection apparatus of claim 10, further comprising:
a valve connected between the static mixer and the primary pipe; and
a compressed spring mounted on the first reservoir, the compressed spring configured to push the medical solution from the static mixer into the primary pipe responsive to the valve being opened.

### Claim 13 (depends on 10)

The medical injection apparatus of claim 10, further comprising one or more elastic membranes, each respective elastic membrane of the one or more elastic membranes mounted on a respective chamber of the one or more chambers and configured to push the medical solution from the respective chamber into each microneedle in a respective microneedle array of the plurality of microneedle arrays responsive to the respective elastic membrane being pushed.

### Claim 14 (depends on 10)

The medical injection apparatus of claim 10, further comprising a plurality of cartridges, each respective cartridge of the plurality of cartridges connected between a respective chamber of the one or more chambers and a respective microneedle in a respective microneedle array of the plurality of microneedle arrays and configured to:
receive a predetermined amount of the medical solution from the respective chamber; and
pass the predetermined amount of the medical solution to the respective microneedle.

### Claim 15

A method for medical injection, comprising:
containing a saline solution in a first reservoir;
containing medicine in a second reservoir;
receiving the saline solution from the first reservoir at a static mixer;
receiving the medicine from the second reservoir at the static mixer;
obtaining, utilizing the static mixer, a medical solution by mixing the medicine with the saline solution;
receiving the medical solution from the static mixer at an injection unit; and
injecting, utilizing the injection unit, the medical solution into a skin of a subject.

### Claim 16 (depends on 14)

The method of claim 14, further comprising:
mounting the first reservoir on the second reservoir; and
mounting the second reservoir on the static mixer.

### Claim 17 (depends on 15)

The method of claim 15, wherein receiving the saline solution from the first reservoir at the static mixer and receiving the medicine from the second reservoir at the static mixer comprise:
pushing the medicine from the second reservoir to the static mixer, comprising:
passing the saline solution from the first reservoir to the second reservoir by opening a first valve connected between the first reservoir and the second reservoir.

### Claim 18 (depends on 16)

The method of claim 16, wherein receiving the medical solution from the static mixer at the injection unit comprises:
passing the medical solution from the static mixer to a primary pipe connected to the static mixer;
passing the medical solution from the primary pipe to a respective chamber of one or more chambers through a respective pipe of one or more pipes connecting the primary pipe to the one or more chambers; and
passing the medical solution from the respective chamber to each respective hollow microneedle in a respective hollow microneedle array of a plurality of hollow microneedle arrays attached to the one or more chambers, a tip of the each respective microneedle extruding from a surface of the respective chamber.

### Claim 19 (depends on 17)

The method of claim 17, wherein injecting the medical solution comprises:
mounting a compressed spring on the first reservoir;
connecting a second valve between the static mixer and the primary pipe; and
pushing, utilizing the compressed spring, the medical solution from the static mixer into and the primary pipe by opening the second valve.

### Claim 20 (depends on 17)

The method of claim 17, wherein injecting the medical solution comprises:
mounting each respective elastic membrane of one or more elastic membranes on a respective chamber of the one or more chambers; and
pushing the medical solution from the respective chamber into each microneedle in a respective microneedle array of the plurality of microneedle arrays by pushing a respective elastic membrane of the one or more elastic membranes.
