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US 2026/0048173 A1Published application
ECO-SKIN: A Kombucha SCOBY-Derived Cellulose Matrix for Accelerated Healing and Antimicrobial Defense
OwnerJonah Goodmaninventor
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OwnerJonah Goodmaninventor
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A reactivatable wound dressing composition comprising a dehydrated bacterial cellulose matrix derived from kombucha fermentation of organic green tea and Manuka honey. The matrix contains embedded dormant colonies of acetic acid bacteria, residual epigallocatechin gallate from green tea, and methylglyoxal from Manuka honey. The dormant bacterial colonies reactivate upon contact with an aqueous kombucha solution, providing antimicrobial activity against pathogens including Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. The dehydrated matrix exhibits natural adhesive properties upon rehydration without requiring additional adhesives. Manufacturing methods involve controlled fermentation at specific pH and temperature parameters, followed by dehydration to preserve bacterial viability. The dressing maintains optimal wound environments by retaining moisture while allowing oxygen exchange, stimulates tissue regeneration, and can be die-cut into various anatomical shapes. Applications include treatment of cuts, burns, surgical incisions, chronic wounds, and skin ulcers with extended wear times of 5-10 hours.
A reactivatable wound dressing composition comprising a dehydrated bacterial cellulose matrix derived from kombucha fermentation of organic green tea and Manuka honey, wherein the matrix comprises bacterial cellulose fibers having dormant colonies of acetic acid bacteria embedded therein, residual epigallocatechin gallate (EGCG) from the organic green tea, and residual methylglyoxal (MGO) from the Manuka honey, wherein the dormant colonies of bacteria are configured to reactivate upon contact with an aqueous rehydration solution to provide antimicrobial activity, and wherein the dehydrated matrix exhibits increased adhesive properties upon rehydration without requiring additional adhesives.
A method for making a reactivatable bacterial cellulose wound dressing, comprising brewing organic green tea in distilled water at a concentration of 0.5% to 1.0% (w/v), cooling the brewed tea solution to a temperature between 25° C. and 30° C., adding medical-grade Manuka honey having a UMF rating of 10+ or greater to the cooled tea solution at a concentration of 8% to 12% by weight/volume, adding a SCOBY starter culture comprising fermented kombucha at a concentration of 10% to 20% by weight/volume, fermenting the mixture under static, aerobic conditions at 28° C.±2° C. Harvest when the bacterial cellulose (BC) concurrently satisfies three criteria:
A method for rehydrating a dehydrated bacterial cellulose wound dressing, comprising storing the dressing in a closed, dual-chamber, vacuum-sealed dual chamber blister pack containing a fixed, pre-measured quantity ranging from 1-50 ml of rehydration solution separated from the dressing by a breakable seal, wherein activation is achieved by rupturing the seal to release the solution and uniformly hydrate the dressing, the configuration providing precise liquid delivery, extended shelf life, and maintenance of sterility until use.
Dependencies are inferred from the claim text.