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US 2026/0041735 A1Published application
Recombinant expression vector for secretion of interleukin-21, and attenuated salmonella strain transformed by means of same
AssigneeThe Industry & Academic Cooperation in Chungnam National University (IAC)
InventorsHyo Jin LEE, Heung Jin JEON, Solbi KIM, Eunji KIM, Minju HAN
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Abstract
The present disclosure relates to a recombinant expression vector for secretion of interleukin-21 and an attenuated Salmonella strain transformed therewith, and provides: a recombinant expression vector comprising an flgM gene and an interleukin-21 gene; an attenuated Salmonella strain transformed therewith; and a pharmaceutical composition for cancer treatment, comprising the attenuated Salmonella strain.
Claims10
A recombinant expression vector comprising:
- an flgM gene;
- an interleukin-21 gene;
- and an flhDC gene, wherein the flgM gene, the interleukin-21 gene, and the flhDC gene are operably linked to an inducible promoter.
Dependencies are inferred from the claim text.