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US 2026/0041708 A1Published application
Ocular lubricant formulations
AssigneeHarrow IP, LLC
InventorsWilliam Stringer, Michael Hanrahan, Patrick H. Witham
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Abstract
Provided herein are formulations and compositions for ocular diseases or disorders such as dry eye disease. Further provided herein are methods for manufacturing ocular formulations and compositions.
Claims20
A method for producing a preservative free ophthalmic composition, comprising:
- preparing a first solution comprising fully hydrolyzed polyvinyl alcohol and partially hydrolyzed polyvinyl alcohol:
- preparing a second solution comprising povidone and one or more excipients:
- adjusting a pH of the second solution to no more than 6.6;
- combining the first solution and the second solution to create the composition;
- and
- filter sterilizing the composition.
3 more elements
A method for producing a preservative free ophthalmic composition, comprising:
- preparing a first solution comprising fully hydrolyzed polyvinyl alcohol and partially hydrolyzed polyvinyl alcohol;
- preparing a second solution comprising povidone, sodium chloride, boric acid, disodium edetate dihydrate, and potassium chloride;
- preparing a third solution comprising glycerin, ethyl alcohol, lecithin, and polysorbate 80;
- adjusting a pH of the second solution to no more than 6.6;
- combining the first solution, the second solution, and the third solution to create the composition;
- and
- filter sterilizing the composition.
4 more elements
Dependencies are inferred from the claim text.