Back to results
US 2026/0041706 A1Published application
Mucus membrane formulations and uses thereof
AssigneeThe Brigham and Women's Hospital, Inc.
InventorsJeffrey M. KARP, Nitin JOSHI, John JOSEPH, Yohannes TESFAIGZI, Helna Mary BABY
Life of this patent
Estimating the term…
Abstract
The invention features a mucosal coating composition including: (i) water: (ii) at least one mucoadhesive polymer/polysaccharide (e.g., a concentration between 0.1-20% w/v); and (iii) at least one surfactant (e.g., a concentration between 0.005-5% w/v). Exhibit long-lasting residence times on mucosal tissues and prophylactic protection against transmucosal pathogens.
Claims52
A mucosal coating composition comprising:
- (i) water;
- (ii) at least one mucoadhesive polymer/polysaccharide;
- and
- (iii) at least one surfactant.
1 more element
A mucosal coating composition comprising:
- (i) water;
- (ii) at least one mucoadhesive polymer/polysaccharide at a concentration between 0.1-20% w/v;
- and
- (iii) at least one surfactant at a concentration between 0.005-5% w/v.
1 more element
A mucosal coating composition comprising:
- (i) water;
- (ii) at least one mucoadhesive polymer/polysaccharide at a concentration between 0.1-10% w/v;
- and
- (iii) at least one surfactant at a concentration between 0.005-5% w/v,
- wherein the composition is a sprayable solution.
2 more elements
A composition comprising:
- (i) water;
- (ii) at least one mucoadhesive polymer/polysaccharide selected from gellan, pectin, and combinations thereof;
- (iii) at least one surfactant selected from benzalkonium chloride, polyoxyethylene 20 sorbitan monooleate, and combinations thereof;
- and
- (iv) phenethyl alcohol.
2 more elements
Dependencies are inferred from the claim text.