Tetrahydronaphthalene derivative

A compound represented by Formula (I) below or a pharmaceutically acceptable salt thereof:

• wherein in Formula (I),
• M represents S, O, or NH;
• R1C represents any structure selected from the group consisting of a 5- to 7-membered aromatic heterocyclic group having a substituent, a C5- to 7-membered aromatic cyclic group having a substituent, and a substituted or unsubstituted 8- to 16-membered polycyclic group, where, the substituent of the 5- to 7-membered aromatic heterocyclic group having the substituent or the C5- to 7-membered aromatic cyclic group having the substituent is 1 to 5 groups independently selected from the group consisting of substituted or unsubstituted benzyloxy, substituted or unsubstituted benzyl, substituted or unsubstituted phenyl, substituted or unsubstituted phenyl C1-6 alkyl, substituted or unsubstituted biphenyl, substituted or unsubstituted pyridyl, substituted or unsubstituted naphthyl, halogen, hydroxy, cyano, amino, C1-6 alkylamino, di-(C1-6 alkyl)amino, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkoxyl, C1-6 alkoxy C1-6 alkyl, nitro, C1-6 haloalkyl, carbamoyl, C1-6 alkylaminocarbonyl, di-(C1-6 alkyl)aminocarbonyl, C1-6 alkoxycarbonyl, C1-6 alkylcarbonyl, COOR10 (R10 is H or C1-6 alkyl, amino, C1-6 alkylamino, or di-(C1-6 alkyl)amino), a 3- to 8-membered non-aromatic heterocycle, morpholinocarbonyl, C3-8 cycloalkyl, C3-8 cycloalkylamino, 3- to 8-membered non-aromatic heterocycle-substituted amino, C1-6 haloalkylsulfanyl, C1-6 haloalkylsulfinyl, C1-6 haloalkylsulfonyl, C1-6 alkylthio, C1-6 alkylsulfinyl, C1-6 alkylsulfonyl, aminosulfonyl, sulfo, sulfamoyl, 18F, 123, boron containing substituents, alpha-emitting nuclides and beta-emitting nuclides,
• where, the substituent of the polycyclic group is 1 to 6 groups independently selected from the group consisting of halogen, hydroxy, cyano, amino, C1-6 alkylamino, di-(C1-6 alkyl)amino, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkoxyl, benzyloxy, benzyl, phenyl, phenyl C1-6 alkyl, C1-6 alkoxy C1-6 alkyl, nitro, C1-6 haloalkyl, carbamoyl, C1-6 alkylaminocarbonyl, di-(C1-6 alkyl)aminocarbonyl, C1-6 alkoxycarbonyl, C1-6 alkylcarbonyl, COOR10 (R10 is H or C1-6 alkyl, amino, C1-6 alkylamino, or di-(C1-6 alkyl)amino), a 3- to 8-membered non-aromatic heterocycle, morpholinocarbonyl, C3-8 cycloalkyl, C3-8 cycloalkylamino, 3- to 8-membered non-aromatic heterocycle-substituted amino, C1-6 haloalkylsulfanyl, C1-6 haloalkylsulfinyl, C1-6 haloalkylsulfonyl, C1-6 alkylthio, C1-6 alkylsulfinyl, C1-6 alkylsulfonyl, aminosulfonyl, sulfo, sulfamoyl, 18F, 123, boron containing substituents, alpha-emitting nuclides and beta-emitting nuclides;
• or,
• M is S, O, NH, or absent (simply represents a single bond), R1C represents 18F, 123I, a substituent including boron, an α radioactive nucleus and/or a β radioactive nucleus;
• R2 represents a group independently selected from the group consisting of halogen, hydroxy, cyano, amino, C1-6 alkylamino, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkoxyl, benzyloxy, benzyl, phenyl, phenyl C1-6 alkyl, C1-6 alkoxy C1-6 alkyl, nitro, C1-6 haloalkyl, carbamoyl, C1-6 alkylaminocarbonyl, di-(C1-6 alkyl)aminocarbonyl, C1-6 alkoxycarbonyl, C1-6 alkylcarbonyl, COOR10 (R10 is H or C1-6 alkyl, amino, C1-6 alkylamino, or di-(C1-6 alkyl)amino), a 3- to 8-membered non-aromatic heterocycle, morpholinocarbonyl, C3-8 cycloalkyl, C3-8 cycloalkylamino, 3- to 8-membered non-aromatic heterocycle-substituted amino, C1-6 haloalkylsulfanyl, C1-6 haloalkylsulfinyl, C1-6 haloalkylsulfonyl, C1-6 alkylthio, C1-6 alkylsulfinyl, C1-6 alkylsulfonyl, aminosulfonyl, sulfo, and sulfamoyl;
• and
• n represents any integer of 0 to 5.