Evaluation of topological complexity and generation of quantitative markers in medical images

A computer-readable storage medium having instructions stored thereon that when executed by a computing system direct the computing system to:

• perform segmentation operations on a reconstructed image to generate a preliminary image of ductal tissue, glandular tissue, or a combination of ductal tissue and glandular tissue;
• apply morphological operations to the preliminary image to generate a ductal and/or glandular image;
• generate a graph from the ductal and/or glandular image;
• and
• generate a quantitative measure of topological complexity from the graph.

A computing system comprising:

• one or more processors;
• and
• a computer-readable storage medium having instructions for adaptive image reconstruction stored thereon that when executed by the one or more processors of the computing system direct the computing system to:
• generate a preliminary reconstruction image using a preliminary reconstruction configuration;
• automatically adjust the preliminary reconstruction configuration to an updated reconstruction configuration, by, at least:
• obtaining preliminary information from the preliminary reconstruction image;
• accessing a database of reconstruction configurations, the database providing a mapping of characteristics of images and objects in the images to reconstruction configurations;
• and
• performing a lookup operation to identify the updated reconstruction configuration based on the preliminary information;
• generate a reconstruction image using the updated reconstruction configuration;
• and
• obtain reconstruction information from the reconstruction image including determining topological complexity of a breast from the reconstruction image.