Device and method for unmixing images
OwnerFrank HECHT, Tatjana STRAKA +1inventors
InventorsFrank HECHT, Tatjana STRAKA, Irmtraud STEINMETZ
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Abstract
A device for unmixing images of samples with fluorescent dyes includes one or more hardware processors. The device is configured to obtain a mixed image of a sample; determine an unmixed image based on the mixed image; determine a noise-map image based on the mixed image; determine a signal-to-noise image based on the unmixed image and the noise map-image; determine a denoised signal-to-noise image based on the signal-to-noise image; and determine a noise-reduced unmixed image of the sample based on the denoised signal-to-noise image and on the noise-map image.
Claims13
A device for unmixing images of samples with fluorescent dyes, the device comprising one or more hardware processors, and being configured to:
- obtain a mixed image of a sample;
- determine an unmixed image based on the mixed image;
- determine a noise-map image based on the mixed image;
- determine a signal-to-noise image based on the unmixed image and the noise map-image;
- determine a denoised signal-to-noise image based on the signal-to-noise image;
- and
- determine a noise-reduced unmixed image of the sample based on the denoised signal-to-noise image and on the noise-map image.
A method for unmixing images of samples with fluorescent dyes, the method comprising:
- obtaining a mixed image of a sample;
- determining an unmixed image based on the mixed image;
- determining a noise-map image based on the mixed image;
- determining a signal-to-noise-image based on the unmixed image and the noise map-image;
- determining a denoised signal-to-noise image based on the signal-to-noise image;
- and
- determining a noise-reduced unmixed image of the sample based the denoised signal-to-noise image and on a noise-map image.
Dependencies are inferred from the claim text.