3D Bioprinted Tissues and Screening Assays Therewith
AssigneeThe Government of The United States, as represented by The Director of the Defense Health Agency
InventorsYantenew Gete, Eric Huy-Dang Nguyen, Rajini Reddy Mudhasani
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Abstract
Disclosed herein are 3D printed vascular tissues and compositions and methods for making the 3D printed vascular tissues. The 3D printed vascular tissues can be used to model vascular tissue damage (e.g., vascular leakage) and in screening assays for agents that cause or inhibit or treat vascular tissue damage.
Claims17
A bioink composition comprising aortic smooth muscle cells and microvascular endothelial cells in an extracellular matrix solution which is a mixture of a gelatin solution, a basement membrane extract solution, and an ECL cell attachment matrix solution.
Dependencies are inferred from the claim text.