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US 2025/0388697 A1Published application
Anti-sod1 nanobodies
AssigneeUniversity of Massachusetts
InventorsDaryl A. Bosco, Miguel Sena Esteves, Meenakshi Sundaram Kumar, Megan E. Fowler-Magaw
Life of this patent
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Abstract
Composition and methods of diagnosing, monitoring, and treating subjects with a motor neuron pathology, such as motor neuron disorders (including but not limited to amyotrophic lateral sclerosis (ALS)) and neuropathies.
Claims18
A single-domain antibody that binds to Superoxide dismutase 1 (SOD1) comprising an amino acid sequence that is at least 80% identical to of any one of SEQ ID NO:
- 2-24.
A vector comprising the nucleic acid molecule according to claim 10.
Dependencies are inferred from the claim text.