# US 2025/0375565 A1 · Method of removing fluid during a medical procedure and fluid removal apparatus > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2025/0375565 A1 - Document ID: US20250375565A1 - Status: Published application - Kind: A1 - Application number: 19/230,244 - Filed: 2025-06-06 - Published: 2025-12-11 - Earliest claimed: 2024-06-06 - Applicants: The Regents of the University of Michigan - Inventors: Neal Podhuturi; Hannah Pham; Eric S. Bui; Demetri A. Monovoukas; Rija R. Awan; Syed Sikander Raza; Yamaan S. Saadeh; Yimeng Zhao; Michael Albdewi - Web page: https://patentgrep.com/patent/US20250375565A1 ## CPC - A61M 1/915: {Constructional details of the pressure distribution manifold} - A61M 1/87: {Details of the aspiration tip, not otherwise provided for} - A61M 1/96: {Suction control thereof} - A61M 39/28: Clamping means for squeezing flexible tubes, e.g. roller clamps {(tube strippers A61M1/83)} - A61M 1/741: {with means for varying suction manually} - A61M 1/743: {by changing the cross-section of the line, e.g. flow regulating valves (A61M1/7413 takes precedence)} - A61M 25/10: Balloon catheters ({A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02;} inflatable balloons for placing stents or stent-grafts A61F2/958 {; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00}) - A61M 2202/0413: Blood - A61M 2210/0693: Brain, cerebrum - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A medical fluid removal apparatus and method uses negative pressure intraoperatively for the induction of hemostasis. The medical fluid removal apparatus includes a tissue interface membrane, a suction compliant body coupled to the tissue interface membrane, and an adapter configured for attachment to a negative pressure source. The suction compliant body is coupled between the tissue interface membrane and the adapter, and the tissue interface membrane is more flexible than the suction compliant body. The method of removing fluid during a medical procedure can include the steps of placing a tissue interface membrane of a medical fluid removal apparatus against a tissue of a patient, and suctioning the fluid beneath the tissue interface membrane or at least partially around the tissue interface membrane and through a suction compliant body of the medical fluid removal apparatus. ## Claims ### Claim 1 A method of removing fluid of a patient during a medical procedure, comprising the steps of: placing a tissue interface membrane of a medical fluid removal apparatus against a tissue of the patient; and suctioning the fluid beneath the tissue interface membrane or at least partially around the tissue interface membrane and through a suction compliant body of the medical fluid removal apparatus. ### Claim 2 (depends on 1) The method of claim 1, wherein the medical procedure is a surgical procedure having one or more incisions. ### Claim 3 (depends on 2) The method of claim 2, wherein the surgical procedure is an intracranial tumor resection and the tissue is multi-contoured brain tissue. ### Claim 4 (depends on 1) The method of claim 1, wherein a suction pressure during the suctioning step allows for hands-free localization of the tissue interface membrane. ### Claim 5 (depends on 1) The method of claim 1, wherein the tissue interface membrane is a perimeter balloon. ### Claim 6 (depends on 1) The method of claim 1, wherein a material of the tissue interface membrane is more flexible than a material of the suction compliant body. ### Claim 7 (depends on 1) The medical fluid removal apparatus of claim 1, wherein the suction compliant body has a non-convex profile that is straight tapered or slopes inward toward an interior suction chamber. ### Claim 8 (depends on 1) The method of claim 1, wherein the medical fluid removal apparatus includes an adapter configured for coupling with a negative pressure source, wherein the suction compliant body is coupled between the tissue interface membrane and the adapter. ### Claim 9 (depends on 8) The method of claim 8, further comprising a pressure valve located between the adapter and the negative pressure source, wherein the pressure valve is manually operable to change an induced negative pressure during the suctioning step. ### Claim 10 (depends on 1) The method of claim 1, wherein an induced negative pressure amount during the suctioning step correlates with a spread area of the tissue interface membrane. ### Claim 11 (depends on 1) The method of claim 1, wherein the fluid includes blood. ### Claim 12 (depends on 11) The method of claim 11, wherein the suctioning step induces hemostasis. ### Claim 13 (depends on 1) The method of claim 1, wherein the placing step is accomplished without direct localization of a bleed origin of the patient. ### Claim 14 (depends on 1) The method of claim 1, wherein the placing step includes deploying the medical fluid removal apparatus through an incision site. ### Claim 15 (depends on 14) The method of claim 14, wherein the tissue interface membrane is a perimeter balloon, further comprising the step of inflating the perimeter balloon after deploying. ### Claim 16 A medical fluid removal apparatus, comprising: a tissue interface membrane; a suction compliant body coupled to the tissue interface membrane; and an adapter configured for attachment to a negative pressure source, wherein the suction compliant body is coupled between the tissue interface membrane and the adapter, and wherein the tissue interface membrane is more flexible than the suction compliant body. ### Claim 17 (depends on 16) The medical fluid removal apparatus of claim 16, wherein the tissue interface membrane is a perimeter balloon. ### Claim 18 (depends on 16) The medical fluid removal apparatus of claim 16, wherein the suction compliant body has a non-convex profile that is straight tapered or slopes inward toward an interior suction chamber. ### Claim 19 (depends on 16) The medical fluid removal apparatus of claim 16, wherein the negative pressure source is an operating room suction tubing. ### Claim 20 (depends on 19) The medical fluid removal apparatus of claim 19, comprising a pressure valve configured to adjust an induced negative pressure. ### Claim 21 (depends on 20) The medical fluid removal apparatus of claim 20, wherein the pressure valve is an adjustable clamp plate configured to clamp the operating room suction tubing. ### Claim 22 (depends on 20) The medical fluid removal apparatus of claim 20, wherein the pressure valve includes an adjustable dial.