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US 2025/0367608 A1Published application
Coatings for field flow fractionation channels to reduce sample sticking
AssigneeWyatt Technology Corporation
InventorsFraser McLeod, Steven P. Trainoff, Anthony Clemens
Life of this patent
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Abstract
A separation mechanism comprises a top plate; a base parallel the top plate; a membrane between the top plate and the base; a channel formed by the top plate and the base; and a low-bind coating at a surface of at least one of the top plate or the membrane along which a sample stream in a flow path flows through the channel to reduce or prevent analyte particles of the sample stream from sticking to the top plate.
Claims20
A separation mechanism, comprising:
- a top plate;
- a base parallel to the top plate;
- a membrane between the top plate and the base;
- a channel formed by the top plate and the base;
- and
- a low-bind coating at a surface of the top plate along which a sample stream in a flow path flows through the channel to reduce or prevent analyte particles of the sample stream from sticking to the top plate.
3 more elements
A separation mechanism, comprising:
- a top plate;
- a base parallel to the top plate;
- a membrane between the top plate and the base;
- a channel formed by the top plate and the base;
- and
- a low-bind coating at a surface of the membrane along which a sample stream in a flow path flows through the channel.
3 more elements
A field flow fractionization system, comprising:
- an injector;
- and
- a separation channel having an input coupled to the injector and an output coupled to a detector, the separation channel further comprising:
- a top plate;
- a base parallel to the top plate;
- a membrane between the top plate and the base;
- a channel formed by the top plate and the base;
- and
- a low-bind coating at a surface of at least one of the top plate or the membrane along which a sample stream in a flow path flows through the channel to reduce or prevent analyte particles of the sample stream from sticking to the top plate.
6 more elements
Dependencies are inferred from the claim text.