# US 2025/0367474 A1 · Graphical representation of radiation therapy > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2025/0367474 A1 - Document ID: US20250367474A1 - Status: Published application - Kind: A1 - Application number: 19/182,086 - Filed: 2025-04-17 - Published: 2025-12-04 - Earliest claimed: 2017-07-26 - Applicants: RefleXion Medical, Inc. - Inventors: Michael Kirk OWENS; Peter Demetri OLCOTT; Rostem BASSALOW - Web page: https://patentgrep.com/patent/US20250367474A1 ## CPC - A61N 5/1071: {for verifying the dose delivered by the treatment plan} - A61B 6/032: {Transmission computed tomography [CT]} - A61B 6/463: {characterised by displaying multiple images or images and diagnostic data on one display} - A61N 5/1045: {using a multi-leaf collimator, e.g. for intensity modulated radiation therapy or IMRT} - A61N 5/1075: {for testing, calibrating, or quality assurance of the radiation treatment apparatus} - A61N 5/1081: {Rotating beam systems with a specific mechanical construction, e.g. gantries} - A61B 6/037: {Emission tomography} - A61N 5/1067: {in real time, i.e. during treatment} - A61N 2005/1074: {Details of the control system, e.g. user interfaces} - A61N 2005/1076: {using a dummy object placed in the radiation field, e.g. phantom} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract Described herein are methods for monitoring the radiation delivery during a radiotherapy delivery session and providing a graphical representation of radiation delivery to an operator (e.g., a clinician, a medical physicist, a radiation therapy technologist). The graphics are updated in real-time, as radiation data is collected by the radiotherapy system, and in some variations, can be updated every 15 minutes or less. A variety of graphical representations (“graphics”) can be used to indicate the status of radiation delivery relative to the planned radiation delivery. Methods optionally include calculating a range of acceptable metric values, generating graphics that represent the range of acceptable metrics values, and generating a graphic that depicts the real-time values of those metrics overlaid with the range of acceptable metrics values. ## Claims ### Claim at position 1 1-26. (canceled) ### Claim 27 A method for calculating a radiation dose delivered to a patient during a radiation delivery session, the method comprising: acquiring radiation measurements from a dose chamber of a linear accelerator; deriving multi-leaf collimator (MLC) leaf opening data of a dynamic MLC using measurements from an MV detector located across from the linear accelerator; and calculating a delivered radiation dose by combining the radiation measurements and MLC leaf opening data with anatomical structure data of a patient, wherein the anatomical structure data comprises anatomical density data. ### Claim 28 (depends on 27) The method of claim 27, further comprising generating a graphic that comprises isodose contours superimposed over an anatomical image of the patient or a phantom. ### Claim 29 (depends on 28) The method of claim 28, wherein the graphic further comprises planned isodose contours superimposed over the anatomical image of the patient. ### Claim 30 (depends on 27) The method of claim 27, wherein acquiring the radiation measurements, driving MLC leaf opening data, and calculating the delivered radiation dose all occur during a radiation delivery session. ### Claim 31 (depends on 27) The method of claim 27, wherein the dose chamber comprises an ionization chamber. ### Claim 32 (depends on 27) The method of claim 27, wherein the dynamic MLC comprises a binary MLC. ### Claim 33 (depends on 27) The method of claim 27, wherein calculating the delivered radiation dose comprises calculating the delivered radiation dose to a target region of the patient. ### Claim 34 (depends on 33) The method of claim 33, wherein calculating the delivered dose comprises calculating the delivered radiation dose at each pixel in the target region, wherein the calculated radiation dose comprises a 2-D dose distribution. ### Claim 35 (depends on 33) The method of claim 33, wherein calculating the delivered dose comprises calculating the delivered radiation dose at each voxel in the target region, wherein the calculated radiation dose comprises a 3-D dose distribution. ### Claim 36 (depends on 27) The method of claim 27, further comprising deriving the anatomical structure data from a CT image. ### Claim 37 (depends on 27) The method of claim 27, wherein anatomical structure data further comprises attenuation coefficients of anatomical structures. ### Claim 38 (depends on 27) The method of claim 27, wherein radiation measurements comprise one or more of radiation pulse intensity, duration, and frequence. ### Claim 39 (depends on 27) The method of claim 27, wherein a firing position of the linear accelerator is determined by a rotatable gantry, and wherein the method further comprises detecting firing positions of the linear accelerator using a gantry position sensor. ### Claim 40 (depends on 39) The method of claim 39, further comprising combining the radiation measurements, MLC leaf opening data, anatomical density data, and detected firing positions to derive a total energy released per unit mass (TERMA) at a target region of the patient, and wherein calculating the delivered radiation dose comprises a convolution superposition dose calculation algorithm that applies a beam energy deposition kernel and the TERMA. ### Claim 41 (depends on 39) The method of claim 39, wherein measurements from the MV detector and radiation measurements from the dose chamber are acquired for multiple detected firing positions of the linear accelerator. ### Claim 42 (depends on 27) The method of claim 27, wherein calculating the delivered radiation dose further comprises using a dose calculation matrix, imaging data acquired during the radiation delivery session, and a radiation-firing matrix. ### Claim 43 (depends on 42) The method of claim 42, wherein the imaging data comprises PET imaging data acquired by one or more PET detectors during the radiation delivery session. ### Claim 44 (depends on 27) The method of claim 27, further comprising generating a graphic that comprises cumulative radiation dose values delivered during the radiation delivery session. ### Claim 45 (depends on 44) The method of claim 44, wherein generating the graphic occurs during the radiation delivery session. ### Claim 46 (depends on 39) The method of claim 39, wherein the gantry position sensor comprises an inclinometer and/or an accelerometer. ### Claim 47 (depends on 41) The method of claim 41, wherein the rotatable gantry is configured to rotate at about 40 RPM or more.